Evidence map›Paper›PMID 34564344›Full record

ArticlePediatric reports2021

COVID 19 Vaccine for Adolescents. Concern about Myocarditis and Pericarditis.

Giuseppe Calcaterra, Jawahar Lal Mehta, Cesare de Gregorio, Gianfranco Butera, Paola Neroni, Vassilios Fanos, Pier Paolo Bassareo

Open access · goldAbstract read
In one paragraph

Article in Pediatric reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

Giuseppe CalcaterraDepartment of Cardiology, Postgraduate Medical School of Cardiology, University of Palermo, 90127 Palermo, Italy.
Jawahar Lal MehtaDepartment of Medicine, University of Arkansas for Medical Sciences and the Veterans Affairs Medical Center, Little Rock, AR 72205, USA.ORCID 0000-0003-0384-2097
Cesare de GregorioDepartment of Clinical and Experimental Medicine, University of Messina, 98125 Messina, Italy.ORCID 0000-0003-3022-266X
Gianfranco ButeraCardiology, Cardiac Surgery, and Heart Lung Transplantation Department, ERN, GUAR HEART, Bambino Gesu' Hospital and Research Institute, IRCCS Rome, 00165 Rome, Italy.
Paola NeroniNeonatal Intensive Care Unit, Department of Surgical Sciences, Policlinico Universitario di Monserrato, University of Cagliari, 09042 Monserrato, Italy.
Vassilios FanosNeonatal Intensive Care Unit, Department of Surgical Sciences, Policlinico Universitario di Monserrato, University of Cagliari, 09042 Monserrato, Italy.
Pier Paolo BassareoDepartment of Cardiology, Mater Misericordiae University Hospital and Our Lady's Children's Hospital Crumlin, University College of Dublin, School of Medicine, D07R2WY Dublin, Ireland.ORCID 0000-0002-8374-0260
University of Cagliari · ITBambino Gesù Children's Hospital · ITMater Misericordiae University Hospital · IEUniversity of Arkansas for Medical Sciences · USUniversity of Messina · ITUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The alarming onset of some cases of myocarditis and pericarditis following the administration of Pfizer-BioNTech and Moderna COVID-19 mRNA-based vaccines in adolescent males has recently been highlighted. All occurred after the second dose of the vaccine. Fortunately, none of patients were critically ill and each was discharged home. Owing to the possible link between these cases and vaccine administration, the US and European health regulators decided to continue to investigate the potential causal relationship between COVID-19 mRNA vaccines and myocarditis. In any case, none of the patients fulfilled the criteria for multi-system inflammatory syndrome or Kawasaki-like disease and there was no evidence of acute SARS-CoV-2 infection.

Indexed as

Kawasaki-like syndromemulti-system inflammatory diseasemyocarditispericarditisSARS-CoV-2vaccine

Identifiers

PMID34564344
PMCPMC8482102
OpenAlexW3198275998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.