Evidence map›Paper›PMID 34564332›Full record

ReviewSports (Basel, Switzerland)2021

Muscle Fiber Type Transitions with Exercise Training: Shifting Perspectives.

Daniel L Plotkin, Michael D Roberts, Cody T Haun, Brad J Schoenfeld

Registry-linked trialAbstract readReview
In one paragraph

Review in Sports (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06112587 (Muscle Function and Strength Training of the Neck and Shoulder in Migraine and Tension-type Headache Patients.), which is not on this map. Cited by 132 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
132citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06112587 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Muscle Function and Strength Training of the Neck and Shoulder in Migraine and Tension-type Headache Patients.

TypeinterventionalSponsorDanish Headache CenterRan2023 to 2024Enrolled30ConditionsMigraine, Tension-Type Headache, Neck PainArmsstrength training
3 · Its place in the literature

Who cites it

132 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  14. Beyond weight loss: the value of physical activity and exercise for improving cardiometabolic risk factors in individuals with overweight and obesity.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2026
    Review
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  20. Brain-muscle axis regulation of neuroinflammation and sarcopenia in Parkinson's disease: the bridging role of lactylation.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review

72 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Daniel L PlotkinHealth Sciences Department, CUNY Lehman College, Bronx, NY 10468, USA.ORCID 0000-0002-8689-5452
Michael D RobertsSchool of Kinesiology, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0002-7359-5362
Cody T HaunFitomics, LLC., Pelham, AL 35124, USA.
Brad J SchoenfeldHealth Sciences Department, CUNY Lehman College, Bronx, NY 10468, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human muscle fibers are generally classified by myosin heavy chain (MHC) isoforms characterized by slow to fast contractile speeds. Type I, or slow-twitch fibers, are seen in high abundance in elite endurance athletes, such as long-distance runners and cyclists. Alternatively, fast-twitch IIa and IIx fibers are abundant in elite power athletes, such as weightlifters and sprinters. While cross-sectional comparisons have shown marked differences between athletes, longitudinal data have not clearly converged on patterns in fiber type shifts over time, particularly between slow and fast fibers. However, not all fiber type identification techniques are created equal and, thus, may limit interpretation. Hybrid fibers, which express more than one MHC type (I/IIa, IIa/IIx, I/IIa/IIx), may make up a significant proportion of fibers. The measurement of the distribution of fibers would necessitate the ability to identify hybrid fibers, which is best done through single fiber analysis. Current evidence using the most appropriate techniques suggests a clear ability of fibers to shift between hybrid and pure fibers as well as between slow and fast fiber types. The context and extent to which this occurs, along with the limitations of current evidence, are discussed herein.

Indexed as

endurance trainingfast-twitch fibersslow-twitch fibersstrength training

Identifiers

PMID34564332
PMCPMC8473039

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.