Evidence map›Paper›PMID 34564315›Full record

ArticleNon-coding RNA2021

17β-Estradiol Regulates miR-9-5p and miR-9-3p Stability and Function in the Aged Female Rat Brain.

Chun K Kim, Megan L Linscott, Sarah Flury, Mengjie Zhang, Mikayla L Newby, Toni R Pak

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Non-coding RNA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Age and 17β-Estradiol (ENon-coding RNA · 2023
    Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chun K KimDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University, Maywood, IL 60153, USA.
Megan L LinscottDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University, Maywood, IL 60153, USA.ORCID 0000-0002-3138-2318
Sarah FluryDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University, Maywood, IL 60153, USA.
Mengjie ZhangDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University, Maywood, IL 60153, USA.
Mikayla L NewbyDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University, Maywood, IL 60153, USA.
Toni R PakDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University, Maywood, IL 60153, USA.ORCID 0000-0002-9685-9754
Loyola University Chicago · US

Funding

Ligand-independent signaling of estrogen receptor beta and the aging brainR01AG033605 · NIA · LOYOLA UNIVERSITY CHICAGO · PI PAK, TONI R. · 2009 to 2021
$3.7M
NIA NIH HHS R01 AG033605NIH HHS AG033605
6 · The paper itself

Abstract

Clinical studies demonstrated that the ovarian hormone 17β-estradiol (E

Indexed as

agingbrainmenopausemiR-9-3pmiR-9-5p

Identifiers

PMID34564315
PMCPMC8482090
OpenAlexW3197936589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.