Evidence map›Paper›PMID 34564200›Full record

ArticleJournal of functional biomaterials2021

A Two-Year Comparative Evaluation of Clinical Performance of a Nanohybrid Composite Resin to a Flowable Composite Resin.

Carelle Badr, Gianrico Spagnuolo, Francesco Amenta, Carlos Khairallah, Syed Sarosh Mahdi, Elie Daher, Gopi Battineni, Nadim Z Baba, Tatiana Zogheib, Syed Saad B Qasim and 3 more

2 registry-linked trialsAbstract read
In one paragraph

Article in Journal of functional biomaterials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06894186 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Comparison of the Functional Properties of Two Injectable Materials in Posterior Teeth: Randomized Clinical Trial

TypeinterventionalSponsorFuture University in EgyptRan2025 to 2026Enrolled52ConditionsClass II Dental Caries, Dental Caries, Injectable CompositeArmsGaenial universal injectable
NCT07491770 nacompletednot on this mapstarted 2025, after this paper: background citation

Clinical Assessment of Viscosity-Modified Composite Resins: Preheated, Sonic Activated, and Flowable Resins in Class V Restorations

TypeinterventionalSponsorTanta UniversityRan2025 to 2026Enrolled36ConditionsComposite Restoration, Class V RestorationsArmsPreheated Nanohybrid Composite Resin (x tra fill), Sonic-Activated Nanohybrid Composite Resin (SonicFill 2®, Kerr, USA), Highly Filled Flowable Composite Resin (G-aenial Universal Flo®, GC Corporation, Japan), Conventional Nanohybrid Composite Resin (NanoPaq®, Germany)
3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
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  3. Effects of adding graphene oxide to composite resin: An in vitrostudy.Acta odontologica latinoamericana : AOL · 2026
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  6. Review
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  13. Color changes of nanocomposites used for clear aligner attachments: an in vitro study.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Carelle BadrDepartment of Esthetic and Restorative Dentistry, School of Dentistry, Saint Joseph University of Beirut, Beirut 1004 2020, Lebanon.
Gianrico SpagnuoloDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", 80131 Napoli, Italy.ORCID 0000-0003-3769-9786
Francesco AmentaCenter of Clinical Research, Telemedicine & Telepharmacy Department, School of Medicinal and Health Products Sciences, University of Camerino, 62032 Camerino, Italy.ORCID 0000-0002-0555-1034
Carlos KhairallahDepartment of Esthetic and Restorative Dentistry, School of Dentistry, Saint Joseph University of Beirut, Beirut 1004 2020, Lebanon.
Syed Sarosh MahdiCenter of Clinical Research, Telemedicine & Telepharmacy Department, School of Medicinal and Health Products Sciences, University of Camerino, 62032 Camerino, Italy.
Elie DaherDepartment of Esthetic and Restorative Dentistry, School of Dentistry, Saint Joseph University of Beirut, Beirut 1004 2020, Lebanon.
Gopi BattineniCenter of Clinical Research, Telemedicine & Telepharmacy Department, School of Medicinal and Health Products Sciences, University of Camerino, 62032 Camerino, Italy.ORCID 0000-0003-0603-2356
Nadim Z BabaAdvanced Specialty Education Program in Implant Dentistry, School of Dentistry, Loma Linda University, Loma Linda, CA 92354, USA.ORCID 0000-0002-6575-3885
Tatiana ZogheibDepartment of Orthodontics and Dentofacial Orthopedics, International University of Catalunya, 08017 Sant Cugat del Vallés, Barcelona, Spain.
Syed Saad B QasimFaculty of Dentistry, University of Kuwait, Kuwait City 12037, Kuwait.
Tony DaherDepartment of Esthetic and Restorative Dentistry, School of Dentistry, Saint Joseph University of Beirut, Beirut 1004 2020, Lebanon.
Nalini ChintalapudiCenter of Clinical Research, Telemedicine & Telepharmacy Department, School of Medicinal and Health Products Sciences, University of Camerino, 62032 Camerino, Italy.ORCID 0000-0003-0818-306X
Carina Mehanna ZogheibDepartment of Esthetic and Restorative Dentistry, School of Dentistry, Saint Joseph University of Beirut, Beirut 1004 2020, Lebanon.ORCID 0000-0002-0706-7262

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis prospective in vivo study aimed to compare the clinical behavior of a flowable composite resin (Genial Universal Flo, GC) and a nanohybrid universal composite resin (Tetric Evo Ceram, Ivoclar Vivadent) used in Class I and II direct esthetic restorations in posterior teeth.

methodsA total of 108 Class I and II direct restorations were performed in patients aged between 20 and 60 years. The originality of this study lies in the fact that both materials were placed in pairs, in the same clinical environment (i.e., the same patient and the same type of tooth). The evaluations were performed now of restoration and after 2-weeks, 6-, 12-, and 24-months intervals using clinical examination, clinical photographs, and radiological examination, according to modified USPHS criteria. Statistical analysis was performed using the Fisher exact test and chi-square analysis.

resultsAt baseline, the universal composite resin showed better esthetic properties such as surface luster, surface staining marginal staining. Both materials regressed significantly over time with no significant difference between groups.

conclusionsBoth flowable and nanohybrid composite resins exhibit acceptable clinical performance. The present 24 months of evaluation of different composites showed that the G-ænial Universal Flo could be an effective esthetic material for posterior restoration. No significant difference between both materials over time concerning surface luster, surface staining, and marginal staining.

Indexed as

class Iclass IIclinical studycomposite resinflowable composite resinnanohybrid composite resin

Identifiers

PMID34564200
PMCPMC8482203

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.