Evidence map›Paper›PMID 34564187›Full record

ArticleMarine drugs2021

Astaxanthin Mitigates Thiacloprid-Induced Liver Injury and Immunotoxicity in Male Rats.

Shimaa M Abou-Zeid, Samira H Aljuaydi, Huda O AbuBakr, Enas A Tahoun, Alessandro Di Cerbo, Mahmoud Alagawany, Samah R Khalil, Mayada R Farag

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Thiacloprid impairs reproductive functions of male Wistar rats.Naunyn-Schmiedeberg's archives of pharmacology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Biology · 2022
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Shimaa M Abou-ZeidDepartment of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, University of Sadat City, Sadat 6012201, Egypt.
Samira H AljuaydiDepartment of Biochemistry and Molecular Biology, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt.
Huda O AbuBakrDepartment of Biochemistry and Molecular Biology, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt.
Enas A TahounDepartment of Pathology, Faculty of Veterinary Medicine, University of Sadat City, Sadat 6012201, Egypt.
Alessandro Di CerboSchool of Biosciences and Veterinary Medicine, University of Camerino, 62024 Matelica, Italy.ORCID 0000-0001-8122-9170
Mahmoud AlagawanyDepartment of Poultry, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt.ORCID 0000-0002-8020-0971
Samah R KhalilForensic Medicine and Toxicology Department, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44511, Egypt.ORCID 0000-0002-5442-6870
Mayada R FaragForensic Medicine and Toxicology Department, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44511, Egypt.
Zagazig University · EGCairo University · EGUniversity of Sadat City · EGUniversità di Camerino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thiacloprid (TCP) is a widely used neonicotinoid insecticide with a probable toxic hazard to animals and human beings. This hazard has intensified the demand for natural compounds to alleviate the expected toxic insults. This study aimed at determining whether astaxanthin (ASX) could mitigate the hepatotoxic effect of TCP and diminish its suppressive effect on immune responses in rats. Animals received TCP by gavage at 62.1 mg/kg (1/10th LD

Indexed as

AnimalsAntioxidantsApoptosisChemical and Drug Induced Liver Injury, ChronicGlutathioneInterleukinsLiverMaleMalondialdehydeNeonicotinoidsNitric Oxide Synthase Type IIOxidative StressRatsSheepSuperoxide DismutaseThiazinesAntioxidantsastaxanthineGlutathioneInterleukinsMalondialdehydeNeonicotinoidsNitric Oxide Synthase Type IISuperoxide DismutasethiaclopridThiazinesTransaminasesXanthophyllsastaxanthinhigh mobility group box protein 1immunityinducible nitric oxide synthaseoxidative stressthiacloprid

Identifiers

PMID34564187
PMCPMC8467938
OpenAlexW3200696094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.