Evidence map›Paper›PMID 34564123›Full record

ArticleJournal of cardiovascular development and disease2021

Efficacy of Lipid-Lowering Therapy during Cardiac Rehabilitation in Patients with Diabetes Mellitus and Coronary Heart Disease.

Thomas Wittlinger, Bernhard Schwaab, Heinz Völler, Christa Bongarth, Viktoria Heinze, Kristina Eckrich, Manju Guha, Michael Richter, Axel Schlitt

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Thomas WittlingerAsklepios Harzkliniken GmbH, Kösliner Strasse 12, 38642 Goslar, Germany.
Bernhard SchwaabMedizinische Fakultät, Universität zu Lübeck, D-23562 Lübeck, Germany.ORCID 0000-0003-4801-1107
Heinz VöllerDepartment of Rehabilitation Medicine, Faculty of Health Sciences Brandenburg, University of Potsdam, D-14469 Potsdam, Germany.
Christa BongarthClinic Höhenried, 82347 Bernried, Germany.
Viktoria HeinzeParacelsus-Harz-Clinic, 06485 Bad Suderode, Germany.
Kristina EckrichClinic Tharandter Wald-Hetzdorf, 09633 Halsbrücke, Germany.
Manju GuhaRehabilitation Clinic Sendesaal, 28329 Bremen, Germany.
Michael RichterCoordination Center for Clinical Studies, Martin Luther-University Halle Wittenberg, 06120 Halle, Germany.
Axel SchlittParacelsus-Harz-Clinic, 06485 Bad Suderode, Germany.
Paracelsus-Harz-Klinik Bad Suderode · DEAsklepios Kliniken Hamburg · DEMartin Luther University Halle-Wittenberg · DEUniversity of Lübeck · DEUniversity of Potsdam · DEWaldburg-Zeil Kliniken · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiac rehabilitation (CR) in patients with coronary heart disease (CHD) increases adherence to a healthy lifestyle and to secondary preventive medication. A notable example of such medication is lipid-lowering therapy (LLT). LLT during CR improves quality of life and prognosis, and thus is particularly relevant for patients with diabetes mellitus, which is a major risk factor for CHD.

designA prospective, multicenter registry study with patients from six rehabilitation centers in Germany.

methodsDuring CR, 1100 patients with a minimum age of 18 years and CHD documented by coronary angiography were included in a LLT registry.

resultsIn 369 patients (33.9%), diabetes mellitus was diagnosed. Diabetic patients were older (65.5 ± 9.0 vs. 62.2 ± 10.9 years,

conclusionWithin 3 months after CR, total and LDL cholesterol were significantly reduced, irrespective of prevalent diabetes mellitus. In addition, CHD patients with diabetes responded faster to LTT than nondiabetic patients, suggesting that diabetic patients benefit more from LLT treatment during CR.

Indexed as

cardiac rehabilitationcoronary heart diseasediabetes mellituslipid-lowering therapy

Identifiers

PMID34564123
PMCPMC8470282
OpenAlexW3170970760

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.