Evidence map›Paper›PMID 34564098›Full record

ReviewJournal of imaging2021

Micro-CT for Biological and Biomedical Studies: A Comparison of Imaging Techniques.

Kleoniki Keklikoglou, Christos Arvanitidis, Georgios Chatzigeorgiou, Eva Chatzinikolaou, Efstratios Karagiannidis, Triantafyllia Koletsa, Antonios Magoulas, Konstantinos Makris, George Mavrothalassitis, Eleni-Dimitra Papanagnou and 5 more

Abstract readReview
In one paragraph

Review in Journal of imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Enamel thickness and density of primary teeth with and without early childhood caries: a micro-computer tomography assessment.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Article
  5. Bone Organoids: A Novel Tool for Modeling and Managing Skeletal Disorders in Diabetes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. The State of High-Resolution Imaging of the Human Inner Ear: A Look Into the Black Box.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kleoniki KeklikoglouHellenic Centre for Marine Research (HCMR), Institute of Marine Biology, Biotechnology and Aquaculture (IMBBC), P.O. Box 2214, 71003 Heraklion, Crete, Greece.ORCID 0000-0002-6693-2033
Christos ArvanitidisHellenic Centre for Marine Research (HCMR), Institute of Marine Biology, Biotechnology and Aquaculture (IMBBC), P.O. Box 2214, 71003 Heraklion, Crete, Greece.
Georgios ChatzigeorgiouHellenic Centre for Marine Research (HCMR), Institute of Marine Biology, Biotechnology and Aquaculture (IMBBC), P.O. Box 2214, 71003 Heraklion, Crete, Greece.
Eva ChatzinikolaouHellenic Centre for Marine Research (HCMR), Institute of Marine Biology, Biotechnology and Aquaculture (IMBBC), P.O. Box 2214, 71003 Heraklion, Crete, Greece.ORCID 0000-0002-7171-5105
Efstratios KaragiannidisFirst Department of Cardiology, AHEPA University Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.ORCID 0000-0001-8328-5942
Triantafyllia KoletsaDepartment of Pathology, Faculty of Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0002-4435-3532
Antonios MagoulasHellenic Centre for Marine Research (HCMR), Institute of Marine Biology, Biotechnology and Aquaculture (IMBBC), P.O. Box 2214, 71003 Heraklion, Crete, Greece.
Konstantinos MakrisMedical School, University of Crete, 71003 Heraklion, Crete, Greece.
George MavrothalassitisMedical School, University of Crete, 71003 Heraklion, Crete, Greece.
Eleni-Dimitra PapanagnouDepartment of Cell Biology and Biophysics, Faculty of Biology, National and Kapodistrian University of Athens (NKUA), 15784 Athens, Greece.ORCID 0000-0003-1277-8007
Andreas S PapazoglouFirst Department of Cardiology, AHEPA University Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.ORCID 0000-0003-4981-8121
Christina PavloudiHellenic Centre for Marine Research (HCMR), Institute of Marine Biology, Biotechnology and Aquaculture (IMBBC), P.O. Box 2214, 71003 Heraklion, Crete, Greece.ORCID 0000-0001-5106-6067
Ioannis P TrougakosDepartment of Cell Biology and Biophysics, Faculty of Biology, National and Kapodistrian University of Athens (NKUA), 15784 Athens, Greece.ORCID 0000-0002-6179-2772
Katerina VasileiadouHellenic Centre for Marine Research (HCMR), Institute of Marine Biology, Biotechnology and Aquaculture (IMBBC), P.O. Box 2214, 71003 Heraklion, Crete, Greece.ORCID 0000-0002-5057-6417
Angeliki VogiatziMedical School, University of Crete, 71003 Heraklion, Crete, Greece.

Funding

Operational Programme "Competitiveness, Entrepreneurship and Innovation" (NSRF 2014-2020) BIOIMAGING-GR (MIS 5002755)
6 · The paper itself

Abstract

Several imaging techniques are used in biological and biomedical studies. Micro-computed tomography (micro-CT) is a non-destructive imaging technique that allows the rapid digitisation of internal and external structures of a sample in three dimensions and with great resolution. In this review, the strengths and weaknesses of some common imaging techniques applied in biological and biomedical fields, such as optical microscopy, confocal laser scanning microscopy, and scanning electron microscopy, are presented and compared with the micro-CT technique through five use cases. Finally, the ability of micro-CT to create non-destructively 3D anatomical and morphological data in sub-micron resolution and the necessity to develop complementary methods with other imaging techniques, in order to overcome limitations caused by each technique, is emphasised.

Indexed as

confocal laser scanning microscopymicro-computed tomographyoptical microscopyscanning electron microscopy

Identifiers

PMID34564098
PMCPMC8470083

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.