Evidence map›Paper›PMID 34564055›Full record

ArticleCell calcium2021

Proton-modulated interactions of ions with transport sites of prokaryotic and eukaryotic NCX prototypes.

Bosmat Refaeli, Stephanie Liu, Reuben Hiller, Moshe Giladi, Carlos R Baiz, Daniel Khananshvili

Open access · greenAbstract read
In one paragraph

Article in Cell calcium, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Exploring the LiCell calcium · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Bosmat RefaeliDepartment of Physiology and Pharmacology, Sackler School of Medicine, Tel-Aviv University, Ramat-Aviv 69978, Israel.
Stephanie LiuDepartment of Chemistry, University of Texas at Austin, Austin, TX 78712-1224, USA.
Reuben HillerDepartment of Physiology and Pharmacology, Sackler School of Medicine, Tel-Aviv University, Ramat-Aviv 69978, Israel.
Moshe GiladiDepartment of Physiology and Pharmacology, Sackler School of Medicine, Tel-Aviv University, Ramat-Aviv 69978, Israel.
Carlos R BaizDepartment of Chemistry, University of Texas at Austin, Austin, TX 78712-1224, USA.
Daniel KhananshviliDepartment of Physiology and Pharmacology, Sackler School of Medicine, Tel-Aviv University, Ramat-Aviv 69978, Israel. Electronic address: dhanan@post.tau.ac.il.
Tel Aviv University · ILThe University of Texas at Austin · US

Funding

Protein structure and dynamics in ultra-heterogeneous environments-RenewalR35GM133359 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI Carlos Raul Baiz · 2019 to 2026
$1.8M
NIGMS NIH HHS R35 GM133359
6 · The paper itself

Abstract

The cytosolic pH decline from 7.2 to 6.9 results in 90% inactivation of mammalian Na

Indexed as

EukaryotaProtonsAnimalsCalciumIonsIon TransportSodium-Calcium ExchangerCalciumIonsProtonsSodium-Calcium ExchangerIon ligationNCX, ion-coordinating residuespH dependenceProton blockTransport rates

Identifiers

PMID34564055
PMCPMC8986329
OpenAlexW3201462850

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.