ArticleOral oncology2021
The utility of intra-oral ultrasound in improving deep margin clearance of oral tongue cancer resections.
Article in Oral oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 34 citations in OpenAlex.
- Ultra-High-Frequency Ultrasound of Oral Cavity Lesions: A Retrospective Pictorial Study with Histopathologic and Clinical Correlation.Diagnostics (Basel, Switzerland) · 2026Article
- Comparing intraoperative ultrasound and wire-guided localisation for skin cancer metastases: impacts on patient safety, outcomes, costs, and implementation.World journal of surgical oncology · 2026Article
- Comparison of intraoral ultrasound, computed tomography and histopathology in assessment of depth of invasion in buccal mucosa cancers - a cross-sectional study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Investigating the Role of Ultrasound in the Diagnosis of Oral Lesions: A Scoping Review.Oral diseases · 2026Article
- GenAI synthesis of histopathological images from Raman imaging for intraoperative tongue squamous cell carcinoma assessment.International journal of oral science · 2025Article
- How Often is Cancer Present in Oral Cavity Re-resections After Initial Positive Margins?The Laryngoscope · 2024Article
- Feasibility of an MR-based digital specimen for tongue cancer resection specimens: a novel approach for margin evaluation.Frontiers in oncology · 2024Article
- Intraoperative rapid assessment of the deep muscle surgical margin of tongue squamous cell carcinoma via Raman spectroscopy.Frontiers in bioengineering and biotechnology · 2024Article
- Intraoperative Ultrasound for Removal of a Fishbone Foreign Body Embedded in the Tongue.Case reports in otolaryngology · 2024Article
- The Reliability of Ultrasonographic Assessment of Depth of Invasion: A Systematic Review with Meta-Analysis.Diagnostics (Basel, Switzerland) · 2023Review
- Overview of Ultrasound in Dentistry for Advancing Research Methodology and Patient Care Quality with Emphasis on Periodontal/Peri-implant Applications.Zeitschrift fur medizinische Physik · 2023Review
- Image-Guided Intraoperative Assessment of Surgical Margins in Oral Cavity Squamous Cell Cancer: A Diagnostic Test Accuracy Review.Diagnostics (Basel, Switzerland) · 2023Review
- Ultrasound-guided resection for squamous cell carcinoma of the buccal mucosa: A feasibility study.Head & neck · 2023Article
- High-Frequency Intraoral Ultrasound for Preoperative Assessment of Depth of Invasion for Early Tongue Squamous Cell Carcinoma: Radiological-Pathological Correlations.International journal of environmental research and public health · 2022Article
- Ultrasound accurately assesses depth of invasion in T1-T2 oral tongue cancer.Laryngoscope investigative otolaryngology · 2022Article
- Review
- The Applications and Potential Developments of Ultrasound in Oral Cancer Management.Technology in cancer research & treatmentReview
Corrections and comments
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Authors and funding
11 authors at 9 institutions in 1 country.
Funding
Abstract
objectivesTo investigate the potential utility of intra-oral ultrasound (IOUS) in guiding deep margin clearance and measuring depth of invasion (DOI) of oral tongue carcinomas (OTC). MATERIALS AND
methodsRetrospective chart review of consecutive patients with T1-T3 OTC who underwent intraoperative ultrasound-guided resection and a comparator group that had undergone resection without the use of IOUS both by a single surgeon. Data was extracted from operative, pathology and radiology reports. Deep margins and DOI were reviewed by a dedicated head and neck pathologist. Correlation between histologic and ultrasound DOI was assessed using Pearson correlation.
resultsA total of 23 patients were included in the study cohort with a comparator group of 21 patients in the control group. None of the patients in the study cohort had a positive (cut-through) deep margin and the mean deep margin clearance was 8.5 ± 4.9 and 6.7 ± 3.8 for the IOUS and non-IOUS groups respectively (p-value 0.18) showing a non-significant improvement in the IOUS group. As a secondary outcome, there was a strong correlation between histologic and ultrasound DOI (0.9449).
conclusionUltrasound appears to be a potentially effective tool in guiding OTC resections. In this small series, IOUS facilitated deep margin clearance and resulted in a non-statistically significant increase in deep margin clearance. Intraoral ultrasound can accurately measure lesional DOI.
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