Evidence map›Paper›PMID 34563869›Full record

ArticleSocial science & medicine (1982)2021

Cumulative stress: A general "s" factor in the structure of stress.

Frank D Mann, Adolfo G Cuevas, Robert F Krueger

Abstract read
In one paragraph

Article in Social science & medicine (1982), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
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  8. When helping helps: benefits of daily advice provision on mood among older adults with life problems.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
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  9. Article
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  13. Stress across the lifecourse and adult mental and physical health outcomes.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2025
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  14. The Continuity of Adversity: Negative Emotionality Links Early Life Adversity With Adult Stressful Life Events.Clinical psychological science : a journal of the Association for Psychological Science · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Frank D MannDepartment of Family, Population, and Preventative Medicine, Stony Brook University, 101 Nicolls Road, Health Sciences Center, Level 3, Room 071, Stony Brook, NY, 11794, USA. Electronic address: frank.mann@stonybrookmedicine.edu.
Adolfo G CuevasDepartment of Community Health, Tufts University, 574 Boston Avenue, Suite 208, Medford, MA, 02155, USA.
Robert F KruegerDepartment of Psychology, University of Minnesota, 7 E River Road, Minneapolis, MN, 55455, USA.

Funding

U19 MIDlife in the United States-Diversity Supplement-WellsU19AG051426 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI CAROL D. RYFF · 2016 to 2026
$74.8M
STATISTICS COREP01AG020166 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI RYFF, CAROL D. · 2002 to 2015
$50.6M
Trauma Exposure and Cognitive Impairment: Understanding Polygenic Liability and the Causative and Moderating Effects of Exposure, PTSD, and Psychiatric Comorbidity in WTC RespondersR21AG074705 · NIA · STATE UNIVERSITY NEW YORK STONY BROOK · PI MANN, FRANK D · 2021 to 2021
$354k
NIA NIH HHS L60 AG074424NIA NIH HHS P01 AG020166NIA NIH HHS R21 AG074705NIA NIH HHS U19 AG051426
6 · The paper itself

Abstract

objectiveThe present study tested a hierarchical model of cumulative stress in a large probability sample of adults from the United States.

methodsExploratory factor analysis (EFA) and confirmatory factor analysis (CFA) models were used to develop and test a hierarchical model of cumulative stress. Structural equation models were used to estimate concurrent associations with demographic factors, polygenic risk scores, and physical health outcomes, as well as prospective associations with physical health outcomes.

resultsA hierarchical model of cumulative stress was the best-fitting model, with a general "s-factor" capturing the tendency for subordinate dimensions of stress to correlate. Associations with demographic factors and polygenic risk scores for physical and psychological phenotypes provide evidence for the convergent validity of a general s-factor of cumulative stress. The general s-factor and subordinate factors of cumulative stress were also associated with physical health outcomes, concurrently and prospectively, including number of chronic conditions, body mass index, and difficulty with activities of daily living.

conclusionsLike other human individual differences, the co-occurrence of social stressors can be understood using a hierarchical model.

Indexed as

Activities of Daily LivingStress, PsychologicalFactor Analysis, StatisticalHumansPsychometricsReproducibility of ResultsCumulative stressEnvironmental riskHealthHierarchyPolygenic risk

Identifiers

PMID34563869
PMCPMC8906193

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.