Evidence map›Paper›PMID 34563787›Full record

ReviewPlacenta2021

A critical assessment of the potential vertical transmission hypotheses: Implications for research on the early-life infection with COVID-19.

Mengqin Yang, Qiuqin Wang, Yulei Song, Minyan Zou, Yan Li, Guihua Xu, Ting Yan, Yamei Bai

Abstract readReview
In one paragraph

Review in Placenta, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mengqin YangSchool of Nursing, Nanjing University of Chinese Medicine, Nanjing, China. Electronic address: ymq1107@126.com.
Qiuqin WangSchool of Nursing, Nanjing University of Chinese Medicine, Nanjing, China. Electronic address: wqq123456@126.com.
Yulei SongSchool of Nursing, Nanjing University of Chinese Medicine, Nanjing, China. Electronic address: 624153904@qq.com.
Minyan ZouSchool of Nursing, Nanjing University of Chinese Medicine, Nanjing, China. Electronic address: 2553261052@qq.com.
Yan LiSchool of Nursing, Nanjing University of Chinese Medicine, Nanjing, China. Electronic address: 2212882409@qq.com.
Guihua XuSchool of Nursing, Nanjing University of Chinese Medicine, Nanjing, China. Electronic address: xgh_88@163.com.
Ting YanNursing Department, Changzhou Second People's Hospital Affiliated to Nanjing Medical University, Changzhou, China. Electronic address: 393395927@qq.com.
Yamei BaiSchool of Nursing, Nanjing University of Chinese Medicine, Nanjing, China. Electronic address: czbym@njucm.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The risk of potential vertical transmission in SARS-CoV-2 infected pregnant women is currently a topic of debate. To explore the correlation between the two, we searched PubMed, Embase®, and Web of Science for studies on vertical transmission of COVID-19. The quality of the studies was evaluated by the Cochrane risk of bias tool. Detailed information of each included case including methods of delivery, protection measures for mothers and neonates at birth, types of specimens, inspection time, results of testing and feeding patterns was collected to assess the possibility of vertical transmission. The results showed that of the 390 neonates reported in 36 studies, 23 were infected with SARS-CoV-2 by potential vertical transmission. From the perspective of virology and pathology, vertical transmission of SARS-CoV-2 was possible via uterus or breastmilk. Some reported potential vertically transmitted neonates could be attributed to horizontal transmission. It is extremely vital to fully elucidate the potential routes of transmission of SARS-CoV-2, implicating clinical practice and nursing to reduce the risk of not only horizontal transmission but also vertical transmission, thus protecting neonates from COVID-19 infection.

Indexed as

Biomedical ResearchCOVID-19FemaleHumansInfant, NewbornInfectious Disease Transmission, VerticalPregnancyPregnancy Complications, InfectiousSARS-CoV-2COVID-19NeonatePreventative proposalsSystematic reviewTransmission routes

Identifiers

PMID34563787
PMCPMC8444478

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.