Evidence map›Paper›PMID 34563188›Full record

Observational studyBMC surgery2021

Adverse events in thyroid surgery: observational study in three surgical units with high volume/year.

Paolo Del Rio, Paolo Carcoforo, Fabio Medas, Elena Bonati, Tommaso Loderer, Margherita Koleva Radica, Piergiorgio Calò

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BMC surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Exploring Post-Thyroidectomy Hypocalcemia in the Background of Thyroiditis- A Comparative Study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
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  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Paolo Del RioUnit of General Surgery, University Hospital of Parma, 14 Gramsci Road, Parma, Italy.
Paolo CarcoforoUnit of General Surgery, University Hospital of Ferrara, Cona, Italy.
Fabio MedasUnit of General Surgery, University Hospital of Cagliari, Cagliari, Italy.
Elena BonatiUnit of General Surgery, University Hospital of Parma, 14 Gramsci Road, Parma, Italy. elena.bonati@unipr.it.
Tommaso LodererUnit of General Surgery, University Hospital of Parma, 14 Gramsci Road, Parma, Italy.
Margherita Koleva RadicaUnit of General Surgery, University Hospital of Ferrara, Cona, Italy.
Piergiorgio CalòUnit of General Surgery, University Hospital of Cagliari, Cagliari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThyroid surgery, performed for benign or malignant pathologies, is one of the most frequently performed procedures and its frequency has even been increasing in recent years. Postoperative bleeding, recurrent laryngeal nerve (RLN) palsy, associated to dysphonia, dysphagia, dyspnea, and hypoparathyroidism represent the most fearful and common complications. We conducted a multicenter, observational study of retrospectively collected data in three high-volume referral centers, enrolling all patients undergone to thyroid surgery between January 2016 and December 2017 in Parma University Hospital, Cagliari University Hospital and Ferrara University Hospital. MATERIALS: Patients were divided into five groups, differentiated thyroid carcinoma, medullary thyroid carcinoma, non-toxic benign pathology, hyperfunctioning benign pathology and NIFTP (Non-invasive Follicular Thyroid neoplasm with Papillary-like nuclear features). A follow up at 7 and 30 days was executed, evaluating the onset of paresthesia, dysphonia and dysphagia. A 6-month follow-up was conducted in cases of early complications.

resultsTotally, 1252 patients were eligible for the study: 907 female and 345 male, with a female to male ratio of 2.6:1 and an average age of 53.428. Total thyroidectomy was performed in 1022 cases, lobectomy in 230. After 6 months we recorded paresthesia in 0.5%, dysphonia in 1.8% and dysphagia in 0.5%.

conclusionOur study confirms once again that a share of morbidity escapes the possibilities of prediction and control by the operator, depending on patient anamnestic, pathological or anatomical factors.

Indexed as

Postoperative ComplicationsThyroid NeoplasmsFemaleHumansMaleMiddle AgedRetrospective StudiesThyroidectomyDysphoniaHypocalcemiaPostoperative bleedingThyroidectomyVocal cord palsy

Identifiers

PMID34563188
PMCPMC8465779

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.