ReviewRespiratory research2021
Oxygenation strategies during flexible bronchoscopy: a review of the literature.
Review in Respiratory research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Efficacy and safety of supraglottic jet oxygenation and ventilation in Chinese patients undergoing bronchoscopic procedures: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- High-Flow Nasal Oxygen versus Noninvasive Ventilation in Acute Exacerbation of Chronic Obstructive Pulmonary Disease Patients: A Meta-Analysis of Randomized Controlled Trials.Canadian respiratory journal · 2023Pooled it
- High-Flow vs. Low-Flow Nasal Cannula in Reducing Hypoxemic Events During Bronchoscopic Procedures: A Systematic Review and Meta-Analysis.Frontiers in medicine · 2022Pooled it
- A comparative study of conventional, High-flow, and jet ventilation via the Wei nasal jet tube for oxygen therapy in patients undergoing bronchoscopic intervention under deep sedation: a randomized controlled trial.Frontiers in medicine · 2026Trial
- Subglottic jet ventilation versus supraglottic jet ventilation for flexible bronchoscopy: a randomized controlled trial.BMC anesthesiology · 2025Trial
- Efficacy and safety of remimazolam-based sedation for intensive care unit patients undergoing fiberoptic bronchoscopy: a single-center prospective randomized controlled study.Respiratory research · 2025Trial
- The safety and efficacy of two different airway management methods for patients undergoing fiberoptic bronchoscopy: a prospective, randomized, controlled clinical trial.BMC anesthesiology · 2025Trial
- Efficacy and Safety of Remimazolam versus Dexmedetomidine and Midazolam in Awake Endotracheal Intubation for Difficult Airway Patients: A Randomized Controlled Study.Drug design, development and therapy · 2025Trial
- Assessment of Conventional Oxygen Therapy, High-Flow Nasal Cannula, and Non-Invasive Ventilation to Secure Bronchofiberoscopy in Patients with Respiratory Acidosis: A Narrative Review and a Proposal for a Protocol in View of a Randomized Multicenter Study.Journal of clinical medicine · 2026Article
- Evaluating lung ventilation via electrical impedance tomography during flexible bronchoscopy with supraglottic jet ventilation: a prospective pilot study.Journal of anesthesia · 2026Article
- The Role of High-Flow Nasal Cannula (HFNC) During Flexible Bronchoscopy in Adult Patients with Moderate Respiratory Dysfunctions: An Observational Study.Journal of clinical medicine · 2026Article
- Bedside bronchoscopy in intubated patients with acute exacerbation of COPD requiring invasive mechanical ventilation: clinical applications, procedural timing, and standardized management.Frontiers in medicine · 2026Review
- Evidence on Non-Invasive Respiratory Support During Flexible Bronchoscopy: A Narrative Review.Journal of clinical medicine · 2025Review
- Practice of oxygenation and respiratory support during fibreoptic bronchoscopy: the OxyFOB study protocol.BMJ open · 2025Article
- Article
- ECMO-assisted bronchoscopic therapy for severe tracheal stenosis: a case report and literature review.BMC pulmonary medicine · 2025Review
- High-flow nasal cannula oxygenation reduces desaturation risk during diagnostic flexible bronchoscopy under deep sedation: a randomized controlled trial.Frontiers in medicine · 2025Article
- Machine learning-based prediction model for bronchoalveolar lavage efficacy in severe pneumonia.Frontiers in medicine · 2025Article
- Oxygenation during Endobronchial Ultrasound: Where do we stand?Sultan Qaboos University medical journal · 2024Article
- Effect of intubation in lateral position on placement of a double-lumen tube in patients undergoing unilateral video-assisted thoracic surgery: a randomied clinical trial.EClinicalMedicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During flexible fiberoptic bronchoscopy (FOB) the arterial partial pressure of oxygen can drop, increasing the risk for respiratory failure. To avoid desaturation episodes during the procedure several oxygenation strategies have been proposed, including conventional oxygen therapy (COT), high flow nasal cannula (HFNC), continuous positive airway pressure (CPAP) and non-invasive ventilation (NIV). By a review of the current literature, we merely describe the clinical practice of oxygen therapies during FOB. We also conducted a pooled data analysis with respect to oxygenation outcomes, comparing HFNC with COT and NIV, separately. COT showed its benefits in patients undergoing FOB for broncho-alveolar lavage (BAL) or brushing for cytology, in those with peripheral arterial oxyhemoglobin saturation < 93% prior to the procedure or affected by obstructive disorder. HFNC is preferable over COT in patients with mild to moderate acute respiratory failure (ARF) undergoing FOB, by improving oxygen saturation and decreasing the episodes of desaturation. On the opposite, CPAP and NIV guarantee improved oxygenation outcomes as compared to HFNC, and they should be preferred in patients with more severe hypoxemic ARF during FOB.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.