Evidence map›Paper›PMID 34563177›Full record

ArticleBMC complementary medicine and therapies2021

Effect of supercritical carbon dioxide fluid extract from Chrysanthemum indicum Linné on bleomycin-induced pulmonary fibrosis.

Juan Nie, Yanlu Liu, Chaoyue Sun, Jingna Zheng, Baoyi Chen, Jianyi Zhuo, Ziren Su, Xiaoping Lai, Jiannan Chen, Jibiao Zheng and 1 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in BMC complementary medicine and therapies, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Efficacy and Safety ofFood science & nutrition · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Juan Nie *School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, 510006, Guangzhou, China.
Yanlu Liu *School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, 510006, Guangzhou, China.
Chaoyue Sun2nd Clinical Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510120, China.
Jingna ZhengSchool of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, 510006, Guangzhou, China.
Baoyi ChenSchool of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, 510006, Guangzhou, China.
Jianyi ZhuoSchool of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, 510006, Guangzhou, China.
Ziren SuSchool of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, 510006, Guangzhou, China.
Xiaoping LaiSchool of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, 510006, Guangzhou, China.
Jiannan ChenSchool of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, 510006, Guangzhou, China.
Jibiao ZhengDepartment of Pharmacy, Central People's Hospital of Zhanjiang, Zhanjiang, 524000, China. 13828280428@163.com.
Yucui LiSchool of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, 510006, Guangzhou, China. liyucui@gzucm.edu.cn.
Guangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs a prevalent type of cryptogenic fibrotic disease with high mortality, idiopathic pulmonary fibrosis (IPF) still lacks effective therapeutic drugs. The compounds extracted from buds and flowers of Chrysanthemum indicum Linné with supercritical-carbon dioxide fluid (CI

methodsRats (Sprague-Dawley, male) were separated into the following groups: normal, model, pirfenidone (50 mg/kg), CI

resultsCI

conclusionThese findings showed that CI

Indexed as

AnimalsAntibiotics, AntineoplasticBleomycinCarbon DioxideChrysanthemumMaleMatrix MetalloproteinasesPlant ExtractsPulmonary FibrosisRatsRats, Sprague-DawleyAntibiotics, AntineoplasticBleomycinCarbon DioxideMatrix MetalloproteinasesPlant ExtractsChrysanthemum indicum LinnéIdiopathic pulmonary fibrosisSupercritical carbon dioxide extractionWnt/β-catenin signalling pathway

Identifiers

PMID34563177
PMCPMC8464116
OpenAlexW3204560242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.