Evidence map›Paper›PMID 34563170›Full record

ArticleBMC musculoskeletal disorders2021

Development and validation of a novel predictive model and web calculator for evaluating transfusion risk after spinal fusion for spinal tuberculosis: a retrospective cohort study.

Shengtao Dong, Wenle Li, Zhi-Ri Tang, Haosheng Wang, Hao Pei, Bo Yuan

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Risk prediction of non-small cell lung cancer in patients with pulmonary nodules: a single-center cohort study based on six machine learning algorithms.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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  6. Surgical treatment of spinal tuberculosis: an updated review.European journal of medical research · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Shengtao Dong *Department of Spine Surgery, Second Affiliated Hospital of Dalian Medical University, Dalian, 116021, China.
Wenle Li *Department of Orthopedics, Xianyang Central Hospital, Xianyang, 712000, China.
Zhi-Ri Tang *School of Physics and Technology, Wuhan University, Wuhan, 430072, China.
Haosheng WangDepartment of Orthopaedics, Second Hospital of Jilin University, Changchun, 130000, China.
Hao PeiDepartment of Orthopaedic Trauma, Second Affiliated Hospital of Dalian Medical University, Dalian, 116021, China.
Bo YuanDepartment of Reparative and Reconstructive Surgery, Second Affiliated Hospital of Dalian Medical University, Dalian, 116021, China. yuanbodl@163.com.
Second Affiliated Hospital of Dalian Medical University · CNDalian Medical University · CNSecond Affiliated Hospital of Jilin University · CNWuhan University · CNXian Yang Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe incidence and adverse events of postoperative blood transfusion in spinal tuberculosis (TB) have attracted increasing attention. Our purpose was to develop a prediction model to evaluate blood transfusion risk after spinal fusion (SF) for spinal TB.

methodsNomogram and machine learning algorithms, support vector machine (SVM), decision tree (DT), multilayer perceptron (MLP), Naive Bayesian (NB), k-nearest neighbors (K-NN) and random forest (RF), were constructed to identified predictors of blood transfusion from all spinal TB cases treated by SF in our department between May 2010 and April 2020. The prediction performance of the models was evaluated by 10-fold cross-validation. We calculated the average AUC and the maximum AUC, then demonstrated the ROC curve with maximum AUC.

resultsThe collected cohort ultimately was consisted of 152 patients, where 56 required allogeneic blood transfusions. The predictors were surgical duration, preoperative Hb, preoperative ABL, preoperative MCHC, number of fused vertebrae, IBL, and anticoagulant history. We obtained the average AUC of nomogram (0.75), SVM (0.62), k-NM (0.65), DT (0.56), NB (0.74), MLP (0.56) and RF (0.72). An interactive web calculator based on this model has been provided ( https://drwenleli.shinyapps.io/STTapp/ ).

conclusionsWe confirmed seven independent risk factors affecting blood transfusion and diagramed them with the nomogram and web calculator.

Indexed as

Spinal FusionTuberculosis, SpinalBayes TheoremBlood TransfusionHumansRetrospective StudiesBlood transfusionMachine learningPrediction modelShiny applicationSpinal fusionSpinal tuberculosis

Identifiers

PMID34563170
PMCPMC8466716
OpenAlexW3202201129

What OpenQuestion holds

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.