Observational studyBMC pulmonary medicine2021
Ultrasound assessment of the rectus femoris in patients with chronic obstructive pulmonary disease predicts poor exercise tolerance: an exploratory study.
Observational study in BMC pulmonary medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 94 citations in OpenAlex.
- The lung-muscle axis in COPD: a conceptual framework integrating evidence, mechanisms, and therapeutic perspectives.Frontiers in immunology · 2026Review
- Pectoral muscle area derived from chest computed tomography to identify quadriceps muscle weakness in COPD.ERJ open research · 2025Article
- Differences in muscle atrophy between the lower limbs and the accessory respiratory muscles in critically ill patients.Journal of medical ultrasonics (2001) · 2025Article
- Smart Bioimpedance Device for the Assessment of Peripheral Muscles in Patients with COPD.Sensors (Basel, Switzerland) · 2024Article
- Longitudinal change in ultrasound-derived rectus femoris cross-sectional area in COPD.ERJ open research · 2024Article
- The role of superb micr ole of superb microvascular imaging in detecting low-gr ascular imaging in detecting low-grade inflammation among adults and those with chronic kidney disease: A preliminary study.Turkish journal of medical sciences · 2023Article
- Associations between bone mineral density and chronic obstructive pulmonary disease.The Journal of international medical research · 2022Article
- Resistin as a Systemic Inflammation-Related Biomarker for Sarcopenia in Patients With Chronic Obstructive Pulmonary Disease.Frontiers in nutrition · 2022Article
- Growth Differentiation Factor-15 as a Biomarker for Sarcopenia in Patients With Chronic Obstructive Pulmonary Disease.Frontiers in nutrition · 2022Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundReduced exercise tolerance is an important clinical feature of chronic obstructive pulmonary disease (COPD) and is associated with poor prognosis. The 6-min walk test (6MWT) is widely used to assess exercise capacity; however, it is not commonly administered in primary medical institutions because it requires a suitable site and professional training. Ultrasound has great potential for evaluating skeletal muscle dimensions in COPD. However, whether skeletal muscle ultrasound can predict impaired exercise tolerance is unclear.
methodsThe study included 154 stable patients with COPD, who were randomly divided into a development set and a validation set. The thickness (RF
resultsStrong correlations were observed between the 6MWD and RF
conclusionsRectus femoris ultrasound has potential clinical application to predict impaired exercise tolerance in patients with COPD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.