Evidence map›Paper›PMID 34563143›Full record

Observational studyBMC ophthalmology2021

Natural course of myopic traction maculopathy and factors influencing progression and visual acuity.

Shiwei Li, Tingting Li, Xiangning Wang, Xuan Cai, Bin Lu, Yan Chen, Chang Liu, Qiang Wu

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Shaping the future of myopia: artificial intelligence for vitreoretinal complications of high and pathologic myopia.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Lamellar macular hole in highly myopic eyes and insights into its development, evolution, and treatment: a mini-review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Shiwei LiDepartment of Ophthalmology, Shanghai Jiaotong University Affiliated Sixth People's Hospital, No. 600 Yishan Rd, 200233, Shanghai, China.
Tingting LiDepartment of Ophthalmology, Shanghai Jiaotong University Affiliated Sixth People's Hospital, No. 600 Yishan Rd, 200233, Shanghai, China.
Xiangning WangDepartment of Ophthalmology, Shanghai Jiaotong University Affiliated Sixth People's Hospital, No. 600 Yishan Rd, 200233, Shanghai, China.
Xuan CaiDepartment of Ophthalmology, Shanghai Jiaotong University Affiliated Sixth People's Hospital, No. 600 Yishan Rd, 200233, Shanghai, China.
Bin LuDepartment of Ophthalmology, Shanghai Jiaotong University Affiliated Sixth People's Hospital, No. 600 Yishan Rd, 200233, Shanghai, China.
Yan ChenDepartment of Ophthalmology, Shanghai Jiaotong University Affiliated Sixth People's Hospital, No. 600 Yishan Rd, 200233, Shanghai, China.
Chang LiuDepartment of Ophthalmology, Shanghai Jiaotong University Affiliated Sixth People's Hospital, No. 600 Yishan Rd, 200233, Shanghai, China.
Qiang WuDepartment of Ophthalmology, Shanghai Jiaotong University Affiliated Sixth People's Hospital, No. 600 Yishan Rd, 200233, Shanghai, China. qiang.wu@shsmu.edu.cn.ORCID http://orcid.org/0000-0002-9169-3791
Shanghai Sixth People's Hospital · CN

Funding

General Program of National Natural Science Foundation of China 81770940
6 · The paper itself

Abstract

backgroundTo describe the natural course of myopic traction maculopathy (MTM) and determine predictive factors for its progression and visual prognosis.

methodsThis retrospective observational study included 113 MTM patients (113 eyes). Best-corrected visual acuity (BCVA) measurements and optical coherence tomography findings were recorded.

resultsOver a mean follow-up of 38.2 ± 11.1 months, 49 of 113 eyes (43.4 %) progressed. The progression rate of outer schisis prominently located in the fovea or posterior staphyloma was significantly higher than that of outer schisis prominently located in paravascular areas (P = 0.0011). MTM with partial posterior vitreous detachment during the follow-up progressed more rapidly than MTM without (P = 0.0447). Patients with older age (> 65 years), without domed-shaped macula and with defects in the ellipsoid zone (EZ) had worse BCVA at the last visit (P = 0.0416, P = 0.0494and P = 0.0130). Multiple linear regression analysis showed that BCVA and defects in the EZ at baseline were significantly associated with the final BCVA (P < 0.0001 and P = < 0.0001, respectively).

conclusionsMTM has a high possibility for progression. Outer schisis located predominantly in the fovea or posterior staphyloma or with partial posterior vitreous detachment exhibits rapid progression. The integrity of the EZ is related to visual prognosis.

Indexed as

Macula LuteaMacular DegenerationMyopia, DegenerativeAgedFollow-Up StudiesHumansMiddle AgedRetrospective StudiesTomography, Optical CoherenceTractionVisual AcuityHigh myopiaMyopic traction maculopathyNatural courseOptical coherence tomographyVisual acuity

Identifiers

PMID34563143
PMCPMC8465690
OpenAlexW3128319121

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.