Evidence map›Paper›PMID 34562980›Full record

ReviewDentistry journal2021

The Current and Potential Application of Medicinal Cannabis Products in Dentistry.

Henry Lowe, Ngeh Toyang, Blair Steele, Joseph Bryant, Wilfred Ngwa, Kaveh Nedamat

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Dentistry journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05498012 (Cannabidiol Effects on Chronic Periodontitis), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05498012 phase1 / phase2completednot on this map

Cannabidiol Effects on Chronic Periodontitis: Monocentric, Randomized, Interventional and Placebo-controlled Study

TypeinterventionalSponsorPalacky UniversityRan2020 to 2022Enrolled90ConditionsChronic PeriodontitisArmsplacebo dental gel, placebo toothpaste, Cannabidiol dental gel, Cannabidiol toothpaste, Placebo toothpaste, Corsodyl dental gel
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Classification and Anti-Pathogens (Basel, Switzerland) · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Cannabidiol and periodontal inflammatory disease: A critical assessment.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2022
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Henry LoweBiotech R & D Institute, University of the West Indies, Mona 99999, Jamaica.
Ngeh ToyangVilotos Pharmaceuticals Inc., Baltimore, MD 21202, USA.ORCID 0000-0001-9683-6192
Blair SteeleBiotech R & D Institute, University of the West Indies, Mona 99999, Jamaica.
Joseph BryantBiotech R & D Institute, University of the West Indies, Mona 99999, Jamaica.
Wilfred NgwaBrigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
Kaveh NedamatSloan School of Management, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
University of the West Indies System · JMBrigham and Women's Hospital · USMassachusetts Institute of Technology · USUniversity of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral and dental diseases are a major global burden, the most common non-communicable diseases (NCDs), and may even affect an individual's general quality of life and health. The most prevalent dental and oral health conditions are tooth decay (otherwise referred to as dental caries/cavities), oral cancers, gingivitis, periodontitis, periodontal (gum) disease, Noma, oro-dental trauma, oral manifestations of HIV, sensitive teeth, cracked teeth, broken teeth, and congenital anomalies such as cleft lip and palate. Herbs have been utilized for hundreds of years in traditional Chinese, African and Indian medicine and even in some Western countries, for the treatment of oral and dental conditions including but not limited to dental caries, gingivitis and toothaches, dental pulpitis, halitosis (bad breath), mucositis, sore throat, oral wound infections, and periodontal abscesses. Herbs have also been used as plaque removers (chew sticks), antimicrobials, analgesics, anti-inflammatory agents, and antiseptics.

Indexed as

cannabinoidsCannabis sativa L.dental cariesgingivitisperiodontitis

Identifiers

PMID34562980
PMCPMC8466648
OpenAlexW3200909916

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.