Evidence map›Paper›PMID 34562948›Full record

ArticleBioengineering (Basel, Switzerland)2021

Success of Thrombectomy in Management of Ischemic Stroke in Two Patients with SynCardia Total Artificial Heart in Bridge-to-Transplantation.

Brendan Le Picault, Charles-Henri David, Pierre-Louis Alexandre, Cédric Lenoble, Philippe Bizouarn, Thierry Lepoivre, Nicolas Groleau, Bertrand Rozec, Hubert Desal, Jean-Christian Roussel and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. The New Frontiers of Artificial Organ Engineering.Bioengineering (Basel, Switzerland) · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Brendan Le PicaultDepartment of Cardiothoracic Surgery, Nantes University Hospital, 44093 Nantes, France.
Charles-Henri DavidDepartment of Cardiothoracic Surgery, Nantes University Hospital, 44093 Nantes, France.
Pierre-Louis AlexandreDepartment of Neuroradiology, Nantes University Hospital, 44093 Nantes, France.
Cédric LenobleDepartment of Neuroradiology, Nantes University Hospital, 44093 Nantes, France.
Philippe BizouarnDepartment of Cardiothoracic Anesthesiology, Nantes University Hospital, 44093 Nantes, France.
Thierry LepoivreDepartment of Cardiothoracic Anesthesiology, Nantes University Hospital, 44093 Nantes, France.
Nicolas GroleauDepartment of Cardiothoracic Anesthesiology, Nantes University Hospital, 44093 Nantes, France.ORCID 0000-0002-8156-2552
Bertrand RozecDepartment of Cardiothoracic Anesthesiology, Nantes University Hospital, 44093 Nantes, France.ORCID 0000-0002-2226-3982
Hubert DesalDepartment of Neuroradiology, Nantes University Hospital, 44093 Nantes, France.
Jean-Christian RousselDepartment of Cardiothoracic Surgery, Nantes University Hospital, 44093 Nantes, France.
Thomas SénageDepartment of Cardiothoracic Surgery, Nantes University Hospital, 44093 Nantes, France.
Nantes Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCirculatory assistance from a SynCardia Total Artificial Heart (SynCardia-TAH) is a reliable bridge-to-transplant solution for patients with end-stage biventricular heart failure. Ischemic strokes affect about 10% of patients with a SynCardia-TAH. We report for the first time in the literature two successful thrombectomies to treat the acute phase of ischemic stroke in two patients treated with a SynCardia-TAH in the bridge-to-transplant (BTT). CASE REPORT: We follow two patients with circulatory support from a SynCardia-TAH in the bridge-to-transplant for terminal biventricular cardiac failure with ischemic stroke during the support period. An early in-hospital diagnosis enables the completion of a mechanical thrombectomy within the first 6 h of the onset of symptoms. There was no intracranial hemorrhagic complication during or after the procedure and the patients fully recovered from neurological deficits, allowing a successful heart transplant.

conclusionThis case report describes the possibility of treating ischemic strokes under a SynCardia-TAH by mechanical thrombectomy following the same recommendations as for the general population with excellent results and without any hemorrhagic complication during or after the procedure.

Indexed as

bridge-to-transplantischemic strokeSynCardiaTAHthrombectomyTotal Artificial Heart

Identifiers

PMID34562948
PMCPMC8469750
OpenAlexW3201409385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.