ArticleBioengineering (Basel, Switzerland)2021
Multiscale Entropy Analysis of Heart Rate Variability in Neonatal Patients with and without Seizures.
Article in Bioengineering (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Quantitative assessment of heart-brain coupling in neonates with hypoxic-ischemic encephalopathy.Frontiers in network physiology · 2026Article
- Advancing entropy analysis for heart rate variability: clinical insights for aging and diabetes.Frontiers in physiology · 2026Review
- Deep learning for suppressing EMG and motion artifacts in armband ECG R-peak detection.Biomedical engineering letters · 2026Article
- Age-dependent patterns of cardiac complexity unveiled by topological data analysis of pediatric heart rate variability.PloS one · 2025Article
- Heart Rate Variability as a Tool for Seizure Prediction: A Scoping Review.Journal of clinical medicine · 2024Article
- Prediction models for lymph node metastasis in cervical cancer based on preoperative heart rate variability.Frontiers in neuroscience · 2024Article
- Artificial Intelligence for Personalized Genetics and New Drug Development: Benefits and Cautions.Bioengineering (Basel, Switzerland) · 2023Article
- Advances in Multivariate and Multiscale Physiological Signal Analysis.Bioengineering (Basel, Switzerland) · 2022Article
- Heart Rate Variability Analysis for Seizure Detection in Neonatal Intensive Care Units.Bioengineering (Basel, Switzerland) · 2022Article
- Multiparametric Investigation of Dynamics in Fetal Heart Rate Signals.Bioengineering (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
The complex physiological dynamics of neonatal seizures make their detection challenging. A timely diagnosis and treatment, especially in intensive care units, are essential for a better prognosis and the mitigation of possible adverse effects on the newborn's neurodevelopment. In the literature, several electroencephalographic (EEG) studies have been proposed for a parametric characterization of seizures or their detection by artificial intelligence techniques. At the same time, other sources than EEG, such as electrocardiography, have been investigated to evaluate the possible impact of neonatal seizures on the cardio-regulatory system. Heart rate variability (HRV) analysis is attracting great interest as a valuable tool in newborns applications, especially where EEG technologies are not easily available. This study investigated whether multiscale HRV entropy indexes could detect abnormal heart rate dynamics in newborns with seizures, especially during ictal events. Furthermore, entropy measures were analyzed to discriminate between newborns with seizures and seizure-free ones. A cohort of 52 patients (33 with seizures) from the Helsinki University Hospital public dataset has been evaluated. Multiscale sample and fuzzy entropy showed significant differences between the two groups (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.