Evidence map›Paper›PMID 34562917›Full record

ArticleBiosensors2021

Immunosensor for Assessing the Welfare of Trainee Guide Dogs.

Hannah Perkins, Michelle Higgins, Marinara Marcato, Paul Galvin, Sofia Rodrigues Teixeira

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hannah PerkinsTyndall National Institute, University College Cork, T12 R5CP Cork, Ireland.
Michelle HigginsTyndall National Institute, University College Cork, T12 R5CP Cork, Ireland.
Marinara MarcatoTyndall National Institute, University College Cork, T12 R5CP Cork, Ireland.ORCID 0000-0002-7938-5227
Paul GalvinTyndall National Institute, University College Cork, T12 R5CP Cork, Ireland.
Sofia Rodrigues TeixeiraTyndall National Institute, University College Cork, T12 R5CP Cork, Ireland.ORCID 0000-0002-3527-4816
University College Cork · IE

Funding

Science Foundation Ireland 12/RC/2289-P2
6 · The paper itself

Abstract

Cortisol is a well established biomarker hormone that regulates many processes in the body and is widely referred to as the stress hormone. Cortisol can be used as a stress marker to allow for detection of stress levels in dogs during the training process. This test will indicate if they will handle the stress under the training or if they might be more suitable as an assistant or companion dog. An immunosensor for detection of cortisol was developed using electrochemical impedance spectroscopy (EIS). The sensor was characterized using chemical and topographical techniques. The sensor was calibrated and its sensitivity determined using a cortisol concentration range of 0.0005 to 50 μg/mL. The theoretical limit of detection was found to be 3.57 fg/mL. When the immunosensor was tested on canine saliva samples, cortisol was detected and measured within the relevant physiological ranges in dogs.

Indexed as

Biosensing TechniquesImmunoassayAnimalsBiomarkersCalibrationDielectric SpectroscopyDogsElectrochemical TechniquesElectrodesHumansHydrocortisoneLimit of DetectionPoint-of-Care SystemsSalivaService AnimalsBiomarkersHydrocortisonecortisoldogsgrapheneimpedancesensorstress

Identifiers

PMID34562917
PMCPMC8465025
OpenAlexW3197218228

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.