Evidence map›Paper›PMID 34562895›Full record

ReviewBiosensors2021

Immunosensing Based on Optical Fiber Technology: Recent Advances.

Maria Simone Soares, Miguel Vidal, Nuno F Santos, Florinda M Costa, Carlos Marques, Sónia O Pereira, Cátia Leitão

Abstract readReview
In one paragraph

Review in Biosensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maria Simone SoaresPhysics Department & I3N, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-2752-1629
Miguel VidalPhysics Department & I3N, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0001-5890-2566
Nuno F SantosPhysics Department & I3N, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0001-9685-7479
Florinda M CostaPhysics Department & I3N, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0001-8729-714X
Carlos MarquesPhysics Department & I3N, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-8596-5092
Sónia O PereiraPhysics Department & I3N, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-4174-7253
Cátia LeitãoPhysics Department & I3N, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-6331-1215

Funding

Fundação para a Ciência e a Tecnologia UIDB/50025/2020 & UIDP/50025/2020; CEECIND/00034/2018 (iFish project); CEEIND/00154/2020, BPD/UI96/5808/2017; BPD/UI96/5177/2020
6 · The paper itself

Abstract

The evolution of optical fiber technology has revolutionized a variety of fields, from optical transmission to environmental monitoring and biomedicine, given their unique properties and versatility. For biosensing purposes, the light guided in the fiber core is exposed to the surrounding media where the analytes of interest are detected by different techniques, according to the optical fiber configuration and biofunctionalization strategy employed. These configurations differ in manufacturing complexity, cost and overall performance. The biofunctionalization strategies can be carried out directly on bare fibers or on coated fibers. The former relies on interactions between the evanescent wave (EW) of the fiber and the analyte of interest, whereas the latter can comprise plasmonic methods such as surface plasmon resonance (SPR) and localized SPR (LSPR), both originating from the interaction between light and metal surface electrons. This review presents the basics of optical fiber immunosensors for a broad audience as well as the more recent research trends on the topic. Several optical fiber configurations used for biosensing applications are highlighted, namely uncladded, U-shape, D-shape, tapered, end-face reflected, fiber gratings and special optical fibers, alongside practical application examples. Furthermore, EW, SPR, LSPR and biofunctionalization strategies, as well as the most recent advances and applications of immunosensors, are also covered. Finally, the main challenges and an outlook over the future direction of the field is presented.

Indexed as

Biosensing TechniquesImmunoassayOptical FibersMetalsSurface Plasmon ResonanceMetalsantibodybiofunctionalizationbiosensoroptical fibersurface plasmon resonance (SPR)

Identifiers

PMID34562895
PMCPMC8472567

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.