Evidence map›Paper›PMID 34562886›Full record

ReviewBiosensors2021

Recent Advances in Microneedle-Based Sensors for Sampling, Diagnosis and Monitoring of Chronic Diseases.

Özgecan Erdem, Ismail Eş, Garbis Atam Akceoglu, Yeşeren Saylan, Fatih Inci

Abstract readReview
In one paragraph

Review in Biosensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Cleanroom-Free Fabrication of Microneedles for Multimodal Drug Delivery.Small (Weinheim an der Bergstrasse, Germany) · 2023
    Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Özgecan ErdemUNAM-National Nanotechnology Research Center, Bilkent University, Ankara 06800, Turkey.
Ismail EşUNAM-National Nanotechnology Research Center, Bilkent University, Ankara 06800, Turkey.ORCID 0000-0002-7369-1039
Garbis Atam AkceogluUNAM-National Nanotechnology Research Center, Bilkent University, Ankara 06800, Turkey.
Yeşeren SaylanDepartment of Chemistry, Hacettepe University, Ankara 06800, Turkey.ORCID 0000-0001-5173-1522
Fatih InciUNAM-National Nanotechnology Research Center, Bilkent University, Ankara 06800, Turkey.ORCID 0000-0002-9918-5038

Funding

Bilim Akademisi BAGEP AwardHacettepe - Bilkent University UNAM Sancar FellowshipTürkiye Bilimsel ve Teknolojik Araştirma Kurumu 118C254Türkiye Bilimsel ve Teknolojik Araştirma Kurumu 118C493Türkiye Bilimsel ve Teknolojik Araştirma Kurumu 120Z335Türkiye Bilimsel ve Teknolojik Araştirma Kurumu 120Z445
6 · The paper itself

Abstract

Chronic diseases (CDs) are noncommunicable illnesses with long-term symptoms accounting for ~70% of all deaths worldwide. For the diagnosis and prognosis of CDs, accurate biomarker detection is essential. Currently, the detection of CD-associated biomarkers is employed through complex platforms with certain limitations in their applicability and performance. There is hence unmet need to present innovative strategies that are applicable to the point-of-care (PoC) settings, and also, provide the precise detection of biomarkers. On the other hand, especially at PoC settings, microneedle (MN) technology, which comprises micron-size needles arranged on a miniature patch, has risen as a revolutionary approach in biosensing strategies, opening novel horizons to improve the existing PoC devices. Various MN-based platforms have been manufactured for distinctive purposes employing several techniques and materials. The development of MN-based biosensors for real-time monitoring of CD-associated biomarkers has garnered huge attention in recent years. Herein, we summarize basic concepts of MNs, including microfabrication techniques, design parameters, and their mechanism of action as a biosensing platform for CD diagnosis. Moreover, recent advances in the use of MNs for CD diagnosis are introduced and finally relevant clinical trials carried out using MNs as biosensing devices are highlighted. This review aims to address the potential use of MNs in CD diagnosis.

Indexed as

Biosensing TechniquesNeedlesPoint-of-Care SystemsChronic DiseaseHumansbiomarkersbiosensorchronic diseasedetection methodsmicroneedles

Identifiers

PMID34562886
PMCPMC8470661

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.