Evidence map›Paper›PMID 34562728›Full record

Trial reportBehaviour research and therapy2021

Cognitive control training for urgency: A pilot randomized controlled trial in an acute clinical sample.

Andrew D Peckham, Jenna P Sandler, Devin Dattolico, R Kathryn McHugh, Daniel S Johnson, Thröstur Björgvinsson, Diego A Pizzagalli, Courtney Beard

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Behaviour research and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03527550 (A Randomized Controlled Trial of Cognitive Control Training for Urgency in a Naturalistic Clinical Setting), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03527550 naterminatednot on this map

A Randomized Controlled Trial of Cognitive Control Training for Urgency in a Naturalistic Clinical Setting

TypeinterventionalSponsorMclean HospitalRan2018 to 2020Enrolled46ConditionsImpulsive Behavior, Mental DisordersArmsCognitive Control Training
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. The Insidious Influence of Stress: An Integrated Model of Stress, Executive Control, and Psychopathology.Clinical psychological science : a journal of the Association for Psychological Science · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andrew D PeckhamMcLean Hospital, 115 Mill Street, Belmont, MA, 02478, USA; Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA. Electronic address: adpeckham@mclean.harvard.edu.
Jenna P SandlerMcLean Hospital, 115 Mill Street, Belmont, MA, 02478, USA; Brandeis University, 415 South Street, Waltham, MA, 02453, USA. Electronic address: jpsandler@brandeis.edu.
Devin DattolicoMcLean Hospital, 115 Mill Street, Belmont, MA, 02478, USA. Electronic address: ddattolico@partners.org.
R Kathryn McHughMcLean Hospital, 115 Mill Street, Belmont, MA, 02478, USA; Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA. Electronic address: kmchugh@mclean.harvard.edu.
Daniel S JohnsonMcLean Hospital, 115 Mill Street, Belmont, MA, 02478, USA. Electronic address: johnson.dan@husky.neu.edu.
Thröstur BjörgvinssonMcLean Hospital, 115 Mill Street, Belmont, MA, 02478, USA; Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA. Electronic address: tbjorgvinsson@mclean.harvard.edu.
Diego A PizzagalliMcLean Hospital, 115 Mill Street, Belmont, MA, 02478, USA; Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA. Electronic address: dap@mclean.harvard.edu.
Courtney BeardMcLean Hospital, 115 Mill Street, Belmont, MA, 02478, USA; Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA. Electronic address: cbeard@mclean.harvard.edu.

Funding

Neuroimaging Studies of Reward Processing in DepressionR37MH068376 · NIMH · UNIVERSITY OF CALIFORNIA-IRVINE · PI Diego A Pizzagalli · 2016 to 2026
$7.4M
Multi level Analysis of Positive Valence Systems Across Mood DisordersR01MH101521 · NIMH · MCLEAN HOSPITAL · PI PIZZAGALLI, DIEGO A · 2013 to 2016
$2.1M
Augmenting hospitalization for SMI by targeting interpretation biasR34MH113600 · NIMH · MCLEAN HOSPITAL · PI ELIAS, COURTNEY BEARD · 2018 to 2020
$991k
A Randomized Controlled Trial of Cognitive Control Training for Urgency in a Naturalistic Clinical SettingF32MH115530 · NIMH · MCLEAN HOSPITAL · PI PECKHAM, ANDREW D · 2017 to 2020
$183k
NIMH NIH HHS F32 MH115530NIMH NIH HHS R01 MH101521NIMH NIH HHS R34 MH113600NIMH NIH HHS R37 MH068376
6 · The paper itself

Abstract

Urgency - rash action in the context of strong emotion - is a facet of impulsivity closely related to many psychological disorders. Deficits in working memory and response inhibition are potential mechanisms underlying urgency, and a previous study showed that cognitive training targeting these domains is efficacious in reducing urgency. However, the feasibility and efficacy of this intervention has not yet been tested in a clinical sample or naturalistic treatment setting. To fill this gap, we conducted a pilot study of cognitive training for individuals reporting high levels of urgency in a partial hospitalization program. We evaluated this intervention in an open trial (n = 20), followed by a randomized controlled trial (n = 46) comparing cognitive training plus treatment as usual to treatment as usual. Results supported the feasibility and acceptability of cognitive training. Participants in the training group showed significant improvement on cognitive tasks, but groups did not differ in urgency. In pooled analyses combining the open trial and RCT, there was a significant reduction in distress intolerance in the training group only. Results indicate the potential benefit of cognitive training for distress intolerance, but do not support the use of cognitive training for urgency in acute clinical settings. The study conducted in the RCT phase of this manuscript is registered on ClinicalTrials.gov (NCT: NCT03527550). The full trial protocol is available on ClinicalTrials.gov.

Indexed as

EmotionsImpulsive BehaviorCognitionHumansPilot ProjectsCognitive trainingInhibitionUrgencyWorking memory

Identifiers

PMID34562728
PMCPMC8555999

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.