Evidence map›Paper›PMID 34562716›Full record

ArticleClinical biomechanics (Bristol, Avon)2021

Adolescents and adults with patellofemoral pain exhibit distinct patellar maltracking patterns.

Aricia Shen, Barry P Boden, Camila Grant, Victor R Carlson, Katharine E Alter, Frances T Sheehan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical biomechanics (Bristol, Avon), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Aricia ShenDepartment of Rehabilitation Medicine, NIH, Bethesda, MD, USA.
Barry P BodenThe Orthopaedic Center, Rockville, MD, USA. Electronic address: bboden@starpower.net.
Camila GrantDepartment of Rehabilitation Medicine, NIH, Bethesda, MD, USA. Electronic address: camila.grant@nih.gov.
Victor R CarlsonDepartment of Rehabilitation Medicine, NIH, Bethesda, MD, USA.
Katharine E AlterDepartment of Rehabilitation Medicine, NIH, Bethesda, MD, USA. Electronic address: kalter@nih.gov.
Frances T SheehanDepartment of Rehabilitation Medicine, NIH, Bethesda, MD, USA. Electronic address: gavellif@cc.nih.gov.
National Institutes of Health · USOrthopaedic Center · US

Funding

Virtual Functional AnatomyZ01CL060062 · CLC · CLINICAL CENTER · PI GAVELLI, FRANCES T · 2004 to 2008
$361k
Intramural NIH HHS Z01 CL060062Intramural NIH HHS Z99 CL999999
6 · The paper itself

Abstract

backgroundChronic idiopathic patellofemoral pain is associated with patellar maltracking in both adolescents and adults. To accurately target the underlying, patient-specific etiology, it is crucial we understand if age-of-pain-onset influences maltracking.

methodsTwenty adolescents (13.9 ± 1.4 years) and 20 adults (28.1 ± 4.9 years) female patients with idiopathic patellofemoral pain (age-of-pain-onset: < 14 and > 18 years of age, respectively) formed the patient cohort. Twenty adolescents and 20 adults (matched for gender, age, and body mass index) formed the control cohort. We captured three-dimensional patellofemoral kinematics during knee flexion-extension using dynamic MRI. Patellar maltracking (deviation in patient-specific patellofemoral kinematics, relative to their respective age-controlled mean values) was the primary outcome measure, which was compared between individuals with adolescent-onset and adult-onset patellofemoral pain using ANOVA and discriminant analysis.

findingsThe female adolescent-onset patellofemoral pain cohort demonstrated increased lateral (P = 0.032), superior (P = 0.007), and posterior (P < 0.001) maltracking, with increased patellar flexion (P < 0.001) and medial spin (P = 0.002), relative to the adult-onset patellofemoral pain cohort. Post-hoc analyses revealed increased lateral shift [mean difference ± 95% confidence interval = -2.9 ± 2.1 mm at 10° knee angle], posterior shift [-2.8 ± 2.1 mm, -3.3 ± 2.3 mm & -3.1 ± 2.4 mm at 10°, 20°& 30°], with greater patellar flexion [3.8 ± 2.6 mm & 5.0 ± 2.8 mm, at 20°& 30°] and medial spin [-2.2 ± 1.7 mm & -3.4 ± 2.3 mm at 20°& 30°]. Axial-plane maltracking accurately differentiated the patient age-of-pain-onset (60-75%, P < 0.001).

interpretationAge-of-pain-onset influences the maltracking patterns seen in patients with patellofemoral pain; with all, but 1, degree of freedom being unique in the adolescent-onset-patellofemoral pain cohort. Clinical awareness of this distinction is crucial for correctly diagnosing a patient's pain etiology and optimizing interventional strategies.

Indexed as

Patellofemoral JointPatellofemoral Pain SyndromeAdolescentAdultBiomechanical PhenomenaFemaleHumansKnee JointPatellaRange of Motion, ArticularChildKinematicsKneeMagnetic resonance imagingpatellaPatellar maltrackingPatellofemoral pain syndromePediatric

Identifiers

PMID34562716
PMCPMC10311915
OpenAlexW3200494207

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.