Evidence map›Paper›PMID 34562228›Full record

ReviewHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2021

Hypertension and Periodontitis: A Joint Report by the Italian Society of Hypertension (SIIA) and the Italian Society of Periodontology and Implantology (SIdP).

Rita Del Pinto, Luca Landi, Guido Grassi, Nicola Marco Sforza, Francesco Cairo, Filippo Citterio, Guerino Paolantoni, Francesco D'Aiuto, Claudio Ferri, Annalisa Monaco and 2 more

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Journal of oral microbiology · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. More than just teeth: How oral health can affect the heart.American heart journal plus : cardiology research and practice · 2024
    Review
  13. May Measure Month 2022 in Italy: A Focus on Fixed-dose Combination, Therapeutic Adherence, and Medical Inertia in a Nationwide Survey.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024
    Article
  14. May Measure Month 2022 in Italy: A Focus on Fixed-dose Combination, Therapeutic Adherence, and Medical Inertia in a Nationwide Survey.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024
    Article
  15. Review
  16. Article
  17. Review
  18. Practical Guidelines for Patients with Hypertension and Periodontitis.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Rita Del PintoUnit of Internal Medicine and Nephrology, Department of Life, Health and Environmental Sciences, Center for Hypertension and Cardiovascular Prevention, San Salvatore Hospital, University of L'Aquila, L'Aquila, Italy.
Luca LandiPrivate Practice, Via della Balduina, 114, 00136, Rome, Italy. lulandi@fastwebnet.it.
Guido GrassiDepartment of Medicine and Surgery, Clinica Medica, University of Milano-Bicocca, Milan, Italy.
Nicola Marco SforzaPrivate Practice, Bologna, Italy.
Francesco CairoResearch Unit in Periodontology and Periodontal Medicine, Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy.
Filippo CitterioDepartment of Surgical Sciences, C.I.R. Dental School, University of Turin, Turin, Italy.
Guerino PaolantoniPrivate Practice, Naples, Italy.
Francesco D'AiutoPeriodontology Unit, UCL Eastman Dental Institute and Hospital, University College London, London, UK.
Claudio FerriUnit of Internal Medicine and Nephrology, Department of Life, Health and Environmental Sciences, Center for Hypertension and Cardiovascular Prevention, San Salvatore Hospital, University of L'Aquila, L'Aquila, Italy. claudio.ferri@univaq.it.
Annalisa MonacoUnit of Oral Diseases, Department of Life, Health and Environmental Sciences, Prevention and Translational Research, Dental Clinic, San Salvatore Hospital, University of L'Aquila, L'Aquila, Italy.
Davide PietropaoliUnit of Oral Diseases, Department of Life, Health and Environmental Sciences, Prevention and Translational Research, Dental Clinic, San Salvatore Hospital, University of L'Aquila, L'Aquila, Italy.
Italian working group on Hypertension, Periodontitis (Hy-Per Group)
San Salvatore Hospital · ITUniversity of L'Aquila · ITEastman Dental Hospital · GBStazione Sperimentale per l'Industria delle Pelli e delle Materie Concianti · ITUniversity of Florence · ITUniversity of Milano-Bicocca · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An accumulating body of evidence supports an independent association between high blood pressure (BP) and periodontitis, possibly mediated by low-grade inflammation. This joint report by the Italian Society of Hypertension (SIIA) and the Italian Society of Periodontology and Implantology (SIdP) working group on Hypertension and Periodontitis (Hy-Per Group) provides a review of the evidence on this topic encompassing epidemiology, biological plausibility, relevance, magnitude, and treatment management. Consensus recommendations are provided for health professionals on how to manage BP in individuals showing signs of poor oral health. In summary, (1) large epidemiological studies highlight that individuals with periodontal diseases have increased risk for high/uncontrolled BP independent of confounders; (2) mechanistically, low-grade inflammation might have a causal role in the association; (3) BP profile and control might benefit from periodontal treatment in pre-hypertensive and hypertensive individuals; (4) oral health status should be evaluated as a potential risk factor for high/uncontrolled BP, and effective oral care should be included as an adjunct lifestyle measure during hypertension management. Further research is needed to optimize BP management in individuals with poor oral health.

Indexed as

HypertensionPeriodontitisDental ImplantationHumansItalyPeriodonticsSocieties, DentalSocieties, MedicalCardiovascular diseasesHypertensionInflammationPeriodontitisRisk factors

Identifiers

PMID34562228
PMCPMC8484186
OpenAlexW3118432747

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.