Evidence map›Paper›PMID 34562143›Full record

ArticleHeart and vessels2022

Right bundle branch block and risk of cardiovascular mortality: the Ibaraki Prefectural Health Study.

Naomi Nakazawa, Tomoko Ishizu, Toshimi Sairenchi, Kazumasa Yamagishi, Nobuyuki Murakoshi, Daishi Nakagawa, Tomofumi Nakatsukasa, Naoto Kawamatsu, Kimi Sato, Masayoshi Yamamoto and 10 more

Abstract read
PubMed Publisher
In one paragraph

Article in Heart and vessels, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Left bundle branch pacing with and without anodal capture: impact on ventricular activation pattern and acute haemodynamics.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  4. Association between complete right bundle branch block and atrial fibrillation development.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 1 country.

Naomi NakazawaDepartment of Clinical Laboratory Medicine, University of Tsukuba, Tsukuba, Japan.
Tomoko IshizuDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Japan. tomoco@md.tsukuba.ac.jp.ORCID http://orcid.org/0000-0003-3794-899X
Toshimi SairenchiIbaraki Health Plaza, Ibaraki Health Service Association, Mito, Japan.
Kazumasa YamagishiDepartment of Public Health Medicine, University of Tsukuba, Tsukuba, Japan.
Nobuyuki MurakoshiDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Japan.
Daishi NakagawaDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Japan.
Tomofumi NakatsukasaDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Japan.
Naoto KawamatsuDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Japan.
Kimi SatoDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Japan.
Masayoshi YamamotoDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Japan.
Tomoko Machino-OtsukaDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Japan.
DongZhu XuDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Japan.
Fujiko IrieDepartment of Health and Welfare, Ibaraki Prefectural Office, Mito, Japan.
Takuji TomizawaIbaraki Health Service Association, Mito, Japan.
Akihiko NogamiDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Japan.
Kazutaka AonumaDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Japan.
Hiroyasu IsoDepartment of Social and Environmental Medicine, Osaka University, Osaka, Japan.
Masaki IedaDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8575, Japan.
Yasushi KawakamiDepartment of Clinical Laboratory Medicine, University of Tsukuba, Tsukuba, Japan.
Hitoshi OtaIbaraki Health Plaza, Ibaraki Health Service Association, Mito, Japan.
University of Tsukuba · JPDokkyo Medical University · JPIbaraki Prefectural Police · JPIbaraki Womens Junior College · JPThe University of Osaka · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Historically, a right bundle branch block has been considered a benign finding in asymptomatic individuals. However, this conclusion is based on a few old studies with small sample sizes. We examined the association between a complete right bundle branch block (CRBBB) and subsequent cardiovascular mortality in the general population in Japan. In this large community-based cohort study, data of 90,022 individuals (mean age, 58.5 ± 10.2 years; 66.2% women) who participated in annual community-based health check-ups were assessed. Subjects were followed up from 1993 to the end of 2016. Cox proportional hazards' models and log-rank tests were used for the data analysis. CRBBB was documented in 1,344 participants (1.5%). Among all included participants, CRBBB was associated with an increased risk of cardiovascular mortality after adjustment for all potential confounders (hazard ratio [HR] 1.21; 95% confidence interval [CI] 1.06-1.38). The increased risk of cardiovascular mortality was particularly evident in women aged < 65 years (HR 2.00; 95% CI 1.34-2.98) and men aged ≥ 65 years (HR 1.28; 95% CI 1.06-1.55). CRBBB is associated with an increased risk of cardiovascular mortality in women aged < 65 years and men aged ≥ 65 years. Clinicians should be aware of the presence of CRBBB in young women and elderly men, even if they exhibit no symptoms.

Indexed as

Bundle-Branch BlockCardiovascular SystemAgedCohort StudiesElectrocardiographyFemaleHumansJapanMaleMiddle AgedCardiovascular mortalityElectrocardiogramEpidemiologyPrognosisRight bundle branch block

Identifiers

PMID34562143
OpenAlexW3200988484

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.