ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2022
Objectively Measured Patterns of Daily Physical Activity and Phenotypic Frailty.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The trial behind it
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Who cites it
27 citing papers in PubMed.
- The association of vitamin D supplementation and serum vitamin D levels with physical activity in older adults: Results from a randomized trial.Journal of the American Geriatrics Society · 2023Trial
- Beyond MVPA minutes: physical activity phenotypes are associated with metabolic profiles in children with obesity.European journal of pediatrics · 2026Article
- Accelerometry-derived activity fragmentation as a predictor of brain atrophy and disability progression in multiple sclerosis.Multiple sclerosis (Houndmills, Basingstoke, England) · 2026Article
- The longitudinal relation between purpose in life and accelerometer-measured physical activity.Mental health and physical activity · 2026Article
- Differences in Physical Activity Assessed by Accelerometry across Hemodialysis Days and Shifts.Clinical journal of the American Society of Nephrology : CJASN · 2026Article
- Relationship between 24-h movement behaviors and frailty-a scoping review.Frontiers in public health · 2026Article
- Site-specific pain dynamics: associations between accelerometer-measured physical activity patterns and pain in older adults.The journal of headache and pain · 2025Article
- Frailty and physical activity: are all physical activity variables equal?The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Associations between dimensions of physical activity (intensity, frequency, duration, and volume) and frailty among middle-aged and older Chinese adults.Journal of exercise science and fitness · 2025Article
- Effects of Malnutrition on the Incidence and Worsening of Frailty in Community-Dwelling Older Adults with Pain.Nutrients · 2025Article
- Associations between sleep duration and quality and physical frailty in community-dwelling older adults: a cross-sectional study.Scientific reports · 2025Article
- Association between physical activity and frailty transitions in middle-aged and older adults: a nationwide longitudinal study.The international journal of behavioral nutrition and physical activity · 2025Article
- The association of physical activity fragmentation with all-cause mortality in Hispanics: a prospective cohort study.Lancet regional health. Americas · 2025Article
- Purpose in life and accelerometer-measured physical activity among older adults.Psychology & health · 2025Article
- Combined association between dietary inflammatory index-related dietary patterns and physical activity with frailty in Chinese older adults: findings from a cross-sectional.Frontiers in public health · 2025Article
- Moderate physical activity and higher frequency are inversely associated with incidence of frailty in middle-aged and older population: a 4-year longitudinal study in Europe.European geriatric medicine · 2024Article
- Predicting physical functioning status in older adults: insights from wrist accelerometer sensors and derived digital biomarkers of physical activity.Journal of the American Medical Informatics Association : JAMIA · 2024Article
- Artificial intelligence-enhanced patient evaluation: bridging art and science.European heart journal · 2024Review
- Physical Activity Fragmentation and Falls in Older Adults: Findings From the National Health and Aging Trends Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Associations between performance-based and patient-reported physical functioning and real-world mobile sensor metrics in older cancer survivors: A pilot study.Journal of geriatric oncology · 2024Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
backgroundSelf-reported low physical activity is a defining feature of phenotypic frailty but does not adequately capture physical activity performed throughout the day. This study examined associations between accelerometer-derived patterns of routine daily physical activity and frailty.
methodsWrist accelerometer and frailty data from 638 participants (mean age 77 [SD = 5.5] years; 44% women) were used to derive 5 physical activity metrics: active minutes/day, sedentary minutes/day, total activity counts/day, activity fragmentation (reciprocal of the average active bout length), and sedentary fragmentation (reciprocal of the average sedentary bout length). Robust, prefrail, and frail statuses were identified using the physical frailty phenotype defined as having 0, 1-2, or ≥3 of the following criterion: weight loss, exhaustion, slowness, self-reported low activity, and weakness. Frailty was collapsed into not frail (robust and prefrail) and frail, and each frailty criteria was dichotomized. Multiple logistic regression was used to model each accelerometer metric. Separate frailty criteria and interactions with age and sex were also examined.
resultsWith higher amounts and intensity of daily activity (more active minutes, fewer sedentary minutes, higher activity counts) and lower activity fragmentation, the odds of frailty were lower compared to robust/prefrail states (p < .02 for all). For interactions, only an age by sedentary fragmentation interaction on the odds of frailty was observed (p = .01). For each separate criteria, accelerometer metrics were associated with odds of slowness, low activity, and weakness.
conclusionLess favorable patterns of objectively measured daily physical activity are associated with frailty and the components of slowness, low self-reported activity, and weakness.
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