Evidence map›Paper›PMID 34561865›Full record

ReviewAnnals of the New York Academy of Sciences2022

Methamphetamine use in the United States: epidemiological update and implications for prevention, treatment, and harm reduction.

Christopher M Jones, Debra Houry, Beth Han, Grant Baldwin, Alana Vivolo-Kantor, Wilson M Compton

Open access · greenAbstract readReview
In one paragraph

Review in Annals of the New York Academy of Sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
121citing papers in PubMed, 6 pooled it
21.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

121 citing papers in PubMed, 6 syntheses or guidelines pooled it, 172 citations in OpenAlex.

  1. Pooled it
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  7. Trial
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  13. Article
  14. The neuroimmune-glutamate hypothesis of addiction.Neuroscience and biobehavioral reviews · 2026
    Review
  15. Article
  16. Article
  17. Modeling the Societal Impact of Methamphetamine-Associated Heart Failure.Journal of the American Heart Association · 2026
    Article
  18. Article
  19. Article
  20. Article

61 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Christopher M JonesNational Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia.
Debra HouryNational Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia.
Beth HanNational Institute on Drug Abuse, National Institutes of Health, Rockville, Maryland.
Grant BaldwinDivision of Overdose Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia.
Alana Vivolo-KantorDivision of Overdose Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia.
Wilson M ComptonNational Institute on Drug Abuse, National Institutes of Health, Rockville, Maryland.
Centers for Disease Control and Prevention · USNational Center for Injury Prevention and Control · USNational Institute on Drug Abuse · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Recent attention has focused on the growing role of psychostimulants, such as methamphetamine in overdose deaths. Methamphetamine is an addictive and potent stimulant, and its use is associated with a range of physical and mental health harms, overdose, and mortality. Adding to the complexity of this resurgent methamphetamine threat is the reality that the increases in methamphetamine availability and harms are occurring in the midst of and intertwined with the ongoing opioid overdose crisis. Opioid involvement in psychostimulant-involved overdose deaths increased from 34.5% of overdose deaths in 2010 to 53.5% in 2019-an increase of more than 50%. This latest evolution of the nation's overdose epidemic poses novel challenges for prevention, treatment, and harm reduction. This narrative review synthesizes what is known about changing patterns of methamphetamine use with and without opioids in the United States, other characteristics associated with methamphetamine use, the contributions of the changing illicit drug supply to use patterns and overdose risk, motivations for couse of methamphetamine and opioids, and awareness of exposure to opioids via the illicit methamphetamine supply. Finally, the review summarizes illustrative community and health system strategies and research opportunities to advance prevention, treatment, and harm reduction policies, programs, and practices.

Indexed as

Drug OverdoseHarm ReductionHumansIllicit DrugsMethamphetamineOpioid EpidemicUnited StatesIllicit DrugsMethamphetaminemethamphetamineopioidoverdose

Identifiers

PMID34561865
PMCPMC9097961
OpenAlexW3199254314

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.