Evidence map›Paper›PMID 34561804›Full record

ArticleEnvironmental science and pollution research international2022

Therapeutic potential of Ferula foetida(Bunge) Regel on gastric ulcer model in rats.

Mohsen Foadoddini, Hossein Javdani, Ali Farahi, Mehran Hosseini

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Sesquiterpenes and Sesquiterpene Derivatives fromAntioxidants (Basel, Switzerland) · 2023
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mohsen FoadoddiniDepartment of Physiology, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran.
Hossein JavdaniDepartment of Molecular Medicine, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran.
Ali FarahiDepartment of Molecular Medicine, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran.
Mehran HosseiniCellular and Molecular Research Center, Department of Anatomical Sciences, Birjand University of Medical Sciences, Birjand, Iran. mehranhosseiny@yahoo.co.in.ORCID http://orcid.org/0000-0002-6793-2035
Birjand University of Medical Sciences · IR

Funding

Birjand University of Medical Sciences 1093
6 · The paper itself

Abstract

The plant Ferula foetida(Bunge) Regel (FFBR) has a long history in Asian traditional medicine. This study aimed to evaluate the ulcer healing potential of FFBR umbel ethanolic extract on acetic acid-induced chronic gastric ulcer in rats. First, the gastric ulcer model was imitated by serosal application of acetic acid in male Wistar rats. Then, the animals were orally fed by ethanolic extract of FFBR umbel (100 mg/kg, 200 mg/kg, and 300 mg/kg), omeprazole (40 mg/kg), or saline for 12 days. Eventually, on the 13th day, animals were sacrificed, and their stomachs were taken out. The macroscopic and microscopic appearances of gastric ulcers and the levels of malondialdehyde (MDA), vascular endothelial growth factor (VEGF), and prostaglandin E

Indexed as

FerulaStomach UlcerAnimalsMaleNF-kappa BRatsRats, WistarVascular Endothelial Growth Factor ANF-kappa BVascular Endothelial Growth Factor AFerulaMalondialdehydeNF-κBProstaglandinsStomach ulcerVascular endothelial growth factor

Identifiers

PMID34561804
OpenAlexW3199657509

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.