ArticleBMC public health2021
Influenza vaccine uptake among at-risk adults (aged 16-64 years) in the UK: a retrospective database analysis.
Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 37 citations in OpenAlex.
- Factors associated with vaccination intentions and uptake among pregnant women in the UK: A scoping review.Human vaccines & immunotherapeutics · 2026Article
- Influencing Factors of Pregnant Women's Willingness to Receive Influenza Vaccination in China.Vaccines · 2025Article
- Navigating the crossroads of health and wealth: socioeconomic inequality in flu vaccination uptake among the elderly in Iran.BMC geriatrics · 2025Article
- Diabetes mortality burden attributable to influenza in China: A population-based time-series analysis.Heliyon · 2025Article
- Knowledge, attitudes, and perceptions of influenza vaccine among pregnant women in Minhang District, Shanghai.Human vaccines & immunotherapeutics · 2024Article
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- Digital Gamification Tool (Let's Control Flu) to Increase Vaccination Coverage Rates: Proposal for Algorithm Development.JMIR research protocols · 2024Article
- Impact of the COVID-19 Pandemic on Influenza Hospital Admissions and Deaths in Wales: Descriptive National Time Series Analysis.JMIR public health and surveillance · 2024Article
- COVID-19 and influenza vaccine uptake among pregnant women in national cohorts of England and Wales.NPJ vaccines · 2024Article
- Public health and economic benefits of seasonal influenza vaccination in risk groups in France, Italy, Spain and the UK: state of play and perspectives.BMC public health · 2024Article
- Influenza vaccination allocation in tropical settings under constrained resources.medRxiv : the preprint server for health sciences · 2024Article
- Impact of a pharmaceutical intervention on influenza vaccination in patients receiving treatment with biological medicines.European journal of hospital pharmacy : science and practice · 2023Article
- Influenza vaccine hesitancy and influencing factors among university students in China: a multicenter cross-sectional survey.Annals of medicine · 2023Article
- Microglial activation, tau and amyloid deposition in TREM2 p.R47H carriers and mild cognitive impairment patients: a multi-modal/multi-tracer PET/MRI imaging study with influenza vaccine immune challenge.Journal of neuroinflammation · 2023Article
- Article
- Knowledge, attitudes, and practices toward seasonal influenza vaccination among healthcare workers and pregnant women in Pakistan: A mixed methods approach.Human vaccines & immunotherapeutics · 2023Article
- Influenza Vaccination Coverage Rates and Determinants in Greek Children until the Age of Ten (2008-2019), the Rhea Mother-Child Cohort.Vaccines · 2023Article
- Article
- Knowledge, attitudes, and practices towards seasonal influenza vaccination among pregnant women and healthcare workers: A cross-sectional survey in Afghanistan.Influenza and other respiratory viruses · 2023Article
- Primary prevention of acute cardiovascular events by influenza vaccination: an observational study.European heart journal · 2023Observational
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn the UK, annual influenza vaccination is currently recommended for adults aged 16-64 years who are in a clinical at-risk group. Despite recommendations, rates of vaccine uptake in the UK have historically been low and below national and international targets. This study aims to analyse vaccine uptake among adults in clinical at-risk groups from the 2015-2016 influenza season to the present.
methodsA retrospective analysis of influenza vaccine coverage in the UK was conducted using data extracted from publicly available sources. Clinically at-risk individuals (as defined by Public Health England), including pregnant women, aged 16-64 years, were included in this study.
resultsInfluenza vaccination coverage rates across the UK in adults aged 16-64 years in a clinical at-risk group have been consistently low over the past 5 years, with only 48.0, 42.4, 44.1 and 52.4% of eligible patients in England, Scotland, Wales and Northern Ireland receiving their annual influenza vaccination during the 2018-2019 influenza season. Influenza vaccine coverage was lowest in patients with morbid obesity and highest in patients with diabetes in 2018-2019. Coverage rates were below current national ambitions of ≥75% in all clinical risk groups. In these clinical at-risk groups, influenza vaccine coverage decreased between 2015 and 2019, and there was considerable regional variation.
conclusionsUptake of the influenza vaccine by adults aged 16-64 years in a clinical at-risk group was substantially below the national ambitions. As a result, many individuals in the UK remain at high risk of developing severe influenza or complications. Given that people who are vulnerable to COVID-19 are also at increased risk of complications from influenza, during the 2020-2021 season, there is a heightened need for healthcare professionals across the UK to address suboptimal vaccine uptake, particularly in at-risk patients. Healthcare professionals and policymakers should consider measures targeted at increasing access to and awareness of the clinical benefits of the influenza vaccine.
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