Evidence map›Paper›PMID 34560371›Full record

ArticleEuropean journal of cancer (Oxford, England : 1990)2021

The European cancer burden in 2020: Incidence and mortality estimates for 40 countries and 25 major cancers.

Tadeusz Dyba, Giorgia Randi, Freddie Bray, Carmen Martos, Francesco Giusti, Nicholas Nicholson, Anna Gavin, Manuela Flego, Luciana Neamtiu, Nadya Dimitrova and 3 more

Abstract read
In one paragraph

Article in European journal of cancer (Oxford, England : 1990), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 338 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
338citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

338 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. SEOM-GETNE-TTCC Clinical guideline thyroid cancer (2023).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Guideline
  2. Guideline
  3. Global quality of life and mortality risk in patients with cancer: a systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Sex-Specific Outcomes after a Negative Colonoscopy in the Finnish Randomized Health Service Study during 2004 to 2016.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Trial
  7. Trial
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  10. Cancer incidence and mortality trends from 2007 to 2021 in Milan.European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2026
    Article
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  14. Review
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  18. Observational
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  20. Article

278 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Tadeusz DybaEuropean Commission, Joint Research Centre (JRC), Ispra, Italy. Electronic address: tadek.dyba@ec.europa.eu.
Giorgia RandiEuropean Commission, Joint Research Centre (JRC), Ispra, Italy. Electronic address: giorgia.randi@ec.europa.eu.
Freddie BrayCancer Surveillance Branch, International Agency for Research on Cancer (IARC), Lyon, France.
Carmen MartosEuropean Commission, Joint Research Centre (JRC), Ispra, Italy.
Francesco GiustiEuropean Commission, Joint Research Centre (JRC), Ispra, Italy.
Nicholas NicholsonEuropean Commission, Joint Research Centre (JRC), Ispra, Italy.
Anna GavinNorthern Ireland Cancer Registry, Belfast, United Kingdom.
Manuela FlegoEuropean Commission, Joint Research Centre (JRC), Ispra, Italy.
Luciana NeamtiuEuropean Commission, Joint Research Centre (JRC), Ispra, Italy.
Nadya DimitrovaEuropean Commission, Joint Research Centre (JRC), Ispra, Italy.
Raquel Negrão CarvalhoEuropean Commission, Joint Research Centre (JRC), Ispra, Italy.
Jacques FerlayCancer Surveillance Branch, International Agency for Research on Cancer (IARC), Lyon, France.
Manola BettioEuropean Commission, Joint Research Centre (JRC), Ispra, Italy.

Funding

World Health Organization 001
6 · The paper itself

Abstract

introductionEurope is an important focus for compiling accurate and up-to-date world cancer statistics owing to its large share of the world's total cancer burden. This article presents incidence and mortality estimates for 25 major cancers across 40 individual countries within European areas and the European Union (EU-27) for the year 2020.

methodsThe estimated national incidence and mortality rates are based on statistical methodology previously applied and verified using the most recently collected incidence data from 151 population-based cancer registries, mortality data and 2020 population estimates.

resultsEstimates reveal 4 million new cases of cancer (excluding non-melanoma skin cancer) and 1.9 million cancer-related deaths. The most common cancers are: breast in women (530,000 cases), colorectum (520,000), lung (480,000) and prostate (470,000). These four cancers account for half the overall cancer burden in Europe. The most common causes of cancer deaths are: lung (380,000), colorectal (250,000), breast (140,000) and pancreatic (130,000) cancers. In EU-27, the estimated new cancer cases are approximately 1.4 million in males and 1.2 million in females, with over 710,000 estimated cancer deaths in males and 560,000 in females.

conclusionThe 2020 estimates provide a basis for establishing priorities in cancer-control measures across Europe. The long-established role of cancer registries in cancer surveillance and the evaluation of cancer control measures remain fundamental in formulating and adapting national cancer plans and pan-European health policies. Given the estimates are built on recorded data prior to the onset of coronavirus disease 2019 (COVID-19), they do not take into account the impact of the pandemic.

Indexed as

AdolescentAdultAgedAged, 80 and overChildChild, PreschoolEuropeFemaleHumansIncidenceInfantInfant, NewbornMaleMiddle AgedNeoplasmsRegistriesCancerCancer registriesEstimationEuropeIncidenceMortality

Identifiers

PMID34560371
PMCPMC8568058

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.