Evidence map›Paper›PMID 34559944›Full record

Trial reportAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2022

Effectiveness of a culturally competent care intervention in reducing disparities in Hispanic live donor kidney transplantation: A hybrid trial.

Elisa J Gordon, Jefferson J Uriarte, Jungwha Lee, Raymong Kang, Michelle Shumate, Richard Ruiz, Amit K Mathur, Daniela P Ladner, Juan Carlos Caicedo

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03276390 (A Culturally Targeted Transplant Program to Increase Live Donation in Hispanics), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03276390 nacompletednot on this map

A Culturally Targeted Transplant Program to Increase Live Donation in Hispanics

TypeinterventionalSponsorNorthwestern UniversityRan2017 to 2021Enrolled11,836ConditionsESRDArmsHispanic Kidney Transplant Program (HKTP)
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Examining post-donation outcomes in Hispanic/Latinx living kidney donors in the United States: A systematic review.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Pooled it
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  19. Racial and ethnic disparities in psychosocial evaluation and liver transplant waitlisting.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elisa J GordonDepartment of Surgery - Division of Transplantation, Center for Health Services and Outcomes Research, Center for Bioethics and Medical Humanities, Northwestern University Feinberg School of Medicine, Chicago, Illinois.ORCID 0000-0003-0969-1998
Jefferson J UriarteCenter for Health Services and Outcomes Research, Northwestern University Feinberg School of Medicine, Chicago, Illinois.ORCID 0000-0002-8507-963X
Jungwha LeeDepartment of Preventive Medicine-Division of Biostatistics, Northwestern University Feinberg School of Medicine, Chicago, Illinois.ORCID 0000-0002-0806-0847
Raymong KangCenter for Community Health, Northwestern University Feinberg School of Medicine, Chicago, Illinois.ORCID 0000-0001-7762-8152
Michelle ShumateDepartment of Communication Studies, Northwestern University, Evanston, Illinois.ORCID 0000-0002-4998-0463
Richard RuizDepartment of Surgery, Baylor University Medical Center, Dallas, Texas.ORCID 0000-0002-5561-518X
Amit K MathurDepartment of Surgery, Mayo Clinic, Scottsdale, Arizona.ORCID 0000-0002-9215-2014
Daniela P LadnerDepartment of Surgery - Division of Transplantation, Northwestern University Feinberg School of Medicine, Chicago, Illinois.ORCID 0000-0001-5526-8272
Juan Carlos CaicedoDepartment of Surgery - Division of Transplantation, Northwestern University Feinberg School of Medicine, Chicago, Illinois.ORCID 0000-0003-3936-6395

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
A Culturally Targeted Transplant Program to Increase Live Donation in HispanicsR01DK104876 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CAICEDO, JUAN C, GORDON, ELISA J · 2016 to 2020
$3.5M
HRSA HHS 234-2005-370011CNCATS NIH HHS UL1 TR001422NIDDK NIH HHS R01 DK104876
6 · The paper itself

Abstract

Hispanic patients receive disproportionately fewer living donor kidney transplants (LDKTs) than non-Hispanic Whites (NHWs). The Northwestern Medicine Hispanic Kidney Transplant Program (HKTP), designed to increase Hispanic LDKTs, was evaluated as a nonrandomized, implementation-effectiveness hybrid trial of patients initiating transplant evaluation at two intervention and two similar control sites. Using a mixed method, observational design, we evaluated the fidelity of the HKTP implementation at the two intervention sites. We tested the impact of the HKTP intervention by evaluating the likelihood of receiving LDKT comparing pre-intervention (January 2011-December 2016) and postintervention (January 2017-March 2020), across ethnicity and centers. The HKTP study included 2063 recipients. Intervention Site A exhibited greater implementation fidelity than intervention Site B. For Hispanic recipients at Site A, the likelihood of receiving LDKTs was significantly higher at postintervention compared with pre-intervention (odds ratio [OR] = 3.17 95% confidence interval [1.04, 9.63]), but not at the paired control Site C (OR = 1.02 [0.61, 1.71]). For Hispanic recipients at Site B, the likelihood of receiving an LDKT did not differ between pre- and postintervention (OR = 0.88 [0.40, 1.94]). The LDKT rate was significantly lower for Hispanics at paired control Site D (OR = 0.45 [0.28, 0.90]). The intervention significantly improved LDKT rates for Hispanic patients at the intervention site that implemented the intervention with greater fidelity. Registration: ClinicalTrials.gov registered (retrospectively) on September 7, 2017 (NCT03276390).

Indexed as

Kidney TransplantationLiving DonorsCulturally Competent CareHumansKidneyRetrospective Studiesclinical research/practiceclinical trialdisparitieseducationethicshealth services and outcomes researchkidney transplantation: living donorkidney transplantation/nephrologysocial sciences

Identifiers

PMID34559944
PMCPMC8813886

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.