Evidence map›Paper›PMID 34559827›Full record

ArticlePloS one2021

Global research priorities for COVID-19 in maternal, reproductive and child health: Results of an international survey.

Melanie Etti, Jackeline Alger, Sofía P Salas, Robin Saggers, Tanusha Ramdin, Margit Endler, Kristina Gemzell-Danielsson, Tobias Alfvén, Yusuf Ahmed, Allison Callejas and 4 more

Abstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Agenda for COVID-19 and long COVID research priorities in Brazil: results of wide consultation and Delphi consensus, 2022-2023.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2025
    Article
  3. European Glaucoma Society research priorities for glaucoma care.The British journal of ophthalmology · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Melanie EttiMakerere University Johns Hopkins University Research Collaboration, Kampala, Uganda.ORCID 0000-0002-3265-635X
Jackeline AlgerFaculty of Medical Sciences, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras.
Sofía P SalasCenter for Bioethics, Faculty of Medicine, Clínica Alemana-Universidad del Desarrollo, Las Condes, Chile.
Robin SaggersCharlotte Maxeke Johannesburg Academic Hospital, University of the Witswatersrand, Johannesburg, South Africa.
Tanusha RamdinCharlotte Maxeke Johannesburg Academic Hospital, University of the Witswatersrand, Johannesburg, South Africa.ORCID 0000-0002-9490-6916
Margit EndlerDepartment of Children's and Women's Health, Karolinska Institutet, Solna, Sweden.
Kristina Gemzell-DanielssonDepartment of Children's and Women's Health, Karolinska Institutet, Solna, Sweden.
Tobias AlfvénDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-2328-3512
Yusuf AhmedLevy Mwanawasa Medical University, Lusaka, Zambia.
Allison CallejasHospital Escuela, Tegucigalpa, Honduras.
Deborah EskenaziUniversidad Peruana de Ciencias Aplicadas & Clínica Delgado, Lima, Peru.ORCID 0000-0001-7879-8022
Asma KhalilFetal Medicine Unit, Department of Obstetrics and Gynaecology, St. George's University Hospitals NHS Foundation Trust, London, United Kingdom.
Kirsty Le DoareInstitute for Infection and Immunity, St George's, University of London, London, United Kingdom.
Maternal, Newborn and Child Health Working Group of the COVID-19 Clinical Research Coalition

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe World Health Organization's "Coordinated Global Research Roadmap: 2019 Novel Coronavirus" outlined the need for research that focuses on the impact of COVID-19 on pregnant women and children. More than one year after the first reported case significant knowledge gaps remain, highlighting the need for a coordinated approach. To address this need, the Maternal, Newborn and Child Health Working Group (MNCH WG) of the COVID-19 Clinical Research Coalition conducted an international survey to identify global research priorities for COVID-19 in maternal, reproductive and child health.

methodThis project was undertaken using a modified Delphi method. An electronic questionnaire was disseminated to clinicians and researchers in three different languages (English, French and Spanish) via MNCH WG affiliated networks. Respondents were asked to select the five most urgent research priorities among a list of 17 identified by the MNCH WG. Analysis of questionnaire data was undertaken to identify key similarities and differences among respondents according to questionnaire language, location and specialty. Following elimination of the seven lowest ranking priorities, the questionnaire was recirculated to the original pool of respondents. Thematic analysis of final questionnaire data was undertaken by the MNCH WG from which four priority research themes emerged.

resultsQuestionnaire 1 was completed by 225 respondents from 29 countries. Questionnaire 2 was returned by 49 respondents. The four priority research themes which emerged from the analysis were 1) access to healthcare during the COVID-19 pandemic, 2) the direct and 3) indirect effects of COVID-19 on pregnant and breastfeeding women and children and 4) the transmission of COVID-19 and protection from infection.

conclusionThe results of these questionnaires indicated a high level of concordance among continents and specialties regarding priority research themes. This prioritized list of research uncertainties, developed to specifically highlight the most urgent clinical needs as perceived by healthcare professionals and researchers, could help funding organizations and researchers to answer the most pressing questions for clinicians and public health professionals during the pandemic. It is hoped that these identified priority research themes can help focus the discussion regarding the allocation of limited resources to enhance COVID-19 research in MNCH globally.

Indexed as

Child HealthMaternal HealthPandemicsReproductive HealthSARS-CoV-2AdultChildChild, PreschoolCOVID-19FemaleHumansInfantInfant, NewbornPregnancy

Identifiers

PMID34559827
PMCPMC8462675

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.