ReviewOcular immunology and inflammation2021
Ocular Adverse Events After COVID-19 Vaccination.
Review in Ocular immunology and inflammation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
92 citing papers in PubMed, 182 citations in OpenAlex.
- Rhino-Orbital Mucormycosis Following COVID-19 Viral Vector Vaccination in an Immunocompetent Patient.Journal of fungi (Basel, Switzerland) · 2026Article
- COVID-19 mRNA vaccination and immune-related adverse events in patients with cancer receiving immune checkpoint inhibitors: a target trial emulation study.Journal for immunotherapy of cancer · 2026Article
- Evaluation of the choroidal structural and vasculature changes following COVID-19 infection and vaccination using optical coherence tomography angiography.International journal of retina and vitreous · 2026Article
- Multiple Evanescent White Dot Syndrome (MEWDS) Following COVID-19 Infection: A Presumed Recurrence.Cureus · 2026Article
- A Case of Vitreous Hemorrhage Possibly Attributable to Retinal Arterial Microaneurysm Following SARS-CoV-2 Vaccination.Clinical case reports · 2025Article
- Case Series: Reactivation of Herpetic Keratitis After COVID-19 mRNA Vaccination During Herpetic Prophylaxis.Vision (Basel, Switzerland) · 2025Article
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- Article
- Clinical characteristics of Graves' disease following COVID-19 infection or vaccination: a multicenter case-control study.Turkish journal of medical sciences · 2025Article
- Ocular neuroinflammatory response secondary to SARS-CoV-2 infection-a review.Frontiers in immunology · 2025Review
- Pharmacovigilance in Vaccines: Importance, Main Aspects, Perspectives, and Challenges-A Narrative Review.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Effect of the COVID-19 pandemic on Vogt-Koyanagi-Harada disease.Scientific reports · 2024Article
- Ischemic and Inflammatory Ocular Adverse Events Following Different Types of Vaccination for COVID-19 and Their Incidence Analysis.Korean journal of ophthalmology : KJO · 2024Article
- Vaccines and the Eye: Current Understanding of the Molecular and Immunological Effects of Vaccination on the Eye.International journal of molecular sciences · 2024Review
- Immunogenicity and Safety of Half-Dose Heterologous mRNA-1273 Booster Vaccination for Adults Primed with the CoronaVacVaccines · 2024Article
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- Long Vax in the Eye: Long Post-COVID Vaccination Syndrome Presenting with Frosted Branch Angiitis.Diseases (Basel, Switzerland) · 2024Article
- The Review of Ophthalmic Symptoms in COVID-19.Clinical ophthalmology (Auckland, N.Z.) · 2024Review
- Macular perfusion changes in people administered two types of COVID-19 vaccines: comment.Arquivos brasileiros de oftalmologia · 2024Article
- Macular perfusion changes in people administered two types of COVID-19 vaccines: optical coherence tomography angiography study.Arquivos brasileiros de oftalmologia · 2024Article
32 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe COVID-19 pandemic has galvanized the development of new vaccines at an unprecedented pace. Since the widespread implementation of vaccination campaigns, reports of ocular adverse effects after COVID-19 vaccinations have emerged. This review summarizes ocular adverse effects possibly associated with COVID-19 vaccination, and discusses their clinical characteristics and management.
methodsNarrative Literature Review.
resultsOcular adverse effects of COVID-19 vaccinations include facial nerve palsy, abducens nerve palsy, acute macular neuroretinopathy, central serous retinopathy, thrombosis, uveitis, multiple evanescent white dot syndrome, Vogt-Koyanagi-Harada disease reactivation, and new-onset Graves' Disease. Studies in current literature are primarily retrospective case series or isolated case reports - these are inherently weak in establishing association or causality. Nevertheless, the described presentations resemble the reported ocular manifestations of the COVID-19 disease itself. Hence, we hypothesize that the human body's immune response to COVID-19 vaccinations may be involved in the pathogenesis of the ocular adverse effects post-COVID-19 vaccination.
conclusionOphthalmologists and generalists should be aware of the possible, albeit rare, ocular adverse effects after COVID-19 vaccination.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.