Evidence map›Paper›PMID 34559527›Full record

ArticleJournal of the American Chemical Society2021

The [4Fe4S] Cluster of Yeast DNA Polymerase ε Is Redox Active and Can Undergo DNA-Mediated Signaling.

Miguel N Pinto, Josy Ter Beek, Levi A Ekanger, Erik Johansson, Jacqueline K Barton

Open access · hybridAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Miguel N PintoDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.
Josy Ter BeekDepartment of Medical Biochemistry and Biophysics, Umeå University, SE-910 87 Umeå, Sweden.
Levi A EkangerDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.ORCID 0000-0001-8131-1641
Erik JohanssonDepartment of Medical Biochemistry and Biophysics, Umeå University, SE-910 87 Umeå, Sweden.
Jacqueline K BartonDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.ORCID 0000-0001-9883-1600
California Institute of Technology · USUmeå University · SE

Funding

DNA Sensing and SignalingR35GM126904 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI BARTON, JACQUELINE K · 2018 to 2021
$2.4M
NIGMS NIH HHS R35 GM126904
6 · The paper itself

Abstract

Many DNA replication and DNA repair enzymes have been found to carry [4Fe4S] clusters. The major leading strand polymerase, DNA polymerase ε (Pol ε) from

Indexed as

DNA Polymerase IIIron-Sulfur ProteinsOxidation-ReductionSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSignal TransductionDNA Polymerase IIIron-Sulfur ProteinsSaccharomyces cerevisiae Proteins

Identifiers

PMID34559527
PMCPMC8499023
OpenAlexW3201300497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.