Evidence map›Paper›PMID 34559440›Full record

ArticleBiochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology2021

Connecting research and teaching introductory cell and molecular biology using an Arabidopsis mutant screen.

Jinjie Liu, Ron Cook, Linda Danhof, David Lopatto, Jon R Stoltzfus, Christoph Benning

Open access · greenAbstract read
In one paragraph

Article in Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. A plant mutant screen CURE integrated with core biology concepts showed effectiveness in course design and students' perceived learning gains.Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jinjie LiuBiological Sciences Program, Michigan State University, East Lansing, Michigan, USA.
Ron CookMSU-DOE Plant Research Laboratory, Michigan State University, East Lansing, Michigan, USA.
Linda DanhofMSU-DOE Plant Research Laboratory, Michigan State University, East Lansing, Michigan, USA.
David LopattoCenter for Teaching, Learning, and Assessment, Grinnell College, Grinnell, Iowa, USA.
Jon R StoltzfusBiological Sciences Program, Michigan State University, East Lansing, Michigan, USA.
Christoph BenningMSU-DOE Plant Research Laboratory, Michigan State University, East Lansing, Michigan, USA.ORCID 0000-0001-8585-3667
Michigan State University · USGrinnell College · US

Funding

Plant Biotechnology for Health and SustainabilityT32GM110523 · NIGMS · MICHIGAN STATE UNIVERSITY · PI LAST, ROBERT LOUIS · 2014 to 2023
$2.2M
MSU Training Program in Plant Biotechnology for Health and Sustainability T32-GM110523NIGMS NIH HHS T32 GM110523
6 · The paper itself

Abstract

A complex research project was translated into a Course-based Undergraduate Research Experience (CURE), which was implemented in sections of an introductory Cell and Molecular Biology laboratory course. The research laboratory generated an engineered plant line producing a growth-inhibiting, lipid-derived plant hormone and mutagenized this line. Students in the CURE cultured the mutagenized plant population and selected and characterized suppressor mutants. They learned to observe phenotypes related to the biosynthesis and perception of the plant hormone and explored the genetic and biochemical basis of these phenotypes. As the students studied the relevant genetic, molecular and biochemical concepts during this CURE, they were able to translate this knowledge into practice and develop scientific arguments. This CURE was a successful collaboration between the teaching lab and the research lab. It benefited both parties as the students had a real-life, deep learning experience in scientific methodology, while the research lab gathered data and materials for further studies.

Indexed as

ArabidopsisBiologyCurriculumHumansKnowledgeLaboratoriesMolecular BiologyStudentsArabidopsiscell and molecular biology courseCourse-based Undergraduate Research Experiencegenotype-phenotypesuppressor mutant

Identifiers

PMID34559440
PMCPMC9214838
OpenAlexW3200749572

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.