Evidence map›Paper›PMID 34559272›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2022

Effects of hyaluronic acid on the bone healing after lateral osteotomy: an experimental animal model.

Guven Yildirim, Kursat Murat Ozcan, Zuleyha Erisgin, Omer Hizli, Cengiz Sivrikaya

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 81% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Guven YildirimDepartment of Otolaryngology, Faculty of Medicine, Giresun University, 28200, Giresun, Turkey.ORCID http://orcid.org/0000-0003-3864-3522
Kursat Murat OzcanDepartment of Otolaryngology, Bilkent City Hospital, 06100, Ankara, Turkey.ORCID http://orcid.org/0000-0002-5262-0565
Zuleyha ErisginDepartment of Histology and Embryology, Faculty of Medicine, Giresun University, 28200, Giresun, Turkey.ORCID http://orcid.org/0000-0003-3523-6542
Omer HizliDepartment of Otolaryngology, Faculty of Medicine, Balikesir University, 10145, Balıkesir, Turkey. hizliomer@gmail.com.ORCID http://orcid.org/0000-0001-6822-2679
Cengiz SivrikayaDepartment of Otolaryngology, Giresun Ilhan Ozdemir Research Hospital, 28200, Giresun, Turkey.ORCID http://orcid.org/0000-0001-8670-5156
Giresun University · TRBalıkesir University · TRBilkent University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePostoperative comfort of the patients undergoing rhinoplasty might be poor because of edema and ecchymosis caused by lateral osteotomy. In this animal experiment, we aimed at performing a quantitative assessment of effects of hyaluronic acid usage on healing process of lateral osteotomy.

methodsFourteen New Zealand rabbits with a weight of 2000-2500 kg and an age of 8-12 weeks were included. Under anesthesia, nasal dorsums were exposed with midline incision and lateral osteotomies on both sides were performed using a 2 mm chisel. A hyaluronic acid-based mesh (Hyalonect

resultsConvergence of fracture lines was observed in 6 (60%) of 10 samples from Hyalonect

conclusionThe effects of hyaluronic acid-based meshes on the bone healing process of the lateral osteotomy area might be investigated furthermore, on more comprehensive studies, as a material facilitating collagen organization and capillary development.

Indexed as

Hyaluronic AcidRhinoplastyAnimalsCollagenEcchymosisHumansModels, AnimalOsteotomyRabbitsCollagenHyaluronic AcidCapillaryCollagenHyaluronic acidLateral osteotomyRhinoplasty

Identifiers

PMID34559272
OpenAlexW3200466053

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.