ArticleMedicine2021
Vertebral artery hypoplasia as an independent risk factor of posterior circulation atherosclerosis and ischemic stroke.
Article in Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Anatomy of vertebral artery hypoplasia and its relationship with clinical implications: a systematic review and meta-analysis of prevalence.Surgical and radiologic anatomy : SRA · 2024Pooled it
- Vertebral Artery Hypoplasia and Posterior Circulation Vulnerability: A Systematic Review of Epidemiological, Hemodynamic, and Clinical Evidence.Neurology international · 2026Review
- Association between alpha 1-antitrypsin levels and intracranial aneurysms: a case-control study.Arquivos de neuro-psiquiatria · 2026Article
- Vessel wall imaging of vertebrobasilar artery configurations associated with posterior circulation infarction and high-risk atherosclerotic plaques.Scientific reports · 2025Article
- Article
- Congenital right subclavian artery aneurysm resection in a 30-year-old woman.Journal of vascular surgery cases and innovative techniques · 2024Article
- Percutaneous Transluminal Angioplasty for Atherosclerotic Stenosis of Vertebral Artery Origin.Journal of clinical medicine · 2024Article
- The association between vertebral artery hypoplasia and fetal-type variants of the posterior cerebral artery with imaging findings among patients with posterior circulation stroke: A single-center cross-sectional study.Health science reports · 2024Article
- Association of Left Vertebral Artery Hypoplasia with Posterior Circulation Stroke and the Functional Outcome of Patients with Atrial Fibrillation-Related Cardioembolic Stroke.AJNR. American journal of neuroradiology · 2023Article
- Association of Vertebral Artery Hypoplasia and Vertebrobasilar Cerebrovascular Accident.Medicina (Kaunas, Lithuania) · 2022Article
- Vertebral Artery Stenosis: A Narrative Review.Cureus · 2022Review
- Clinical Characteristics of Patients with Vertebral Artery Hypoplasia.International journal of environmental research and public health · 2022Article
- Association of Systemic Hemodynamics and Endothelial Dysfunction With Clinical Phenotypes in Sensorineural Hearing Loss With Vertigo: A Cross-Sectional Analysis.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-facialeObservational
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
abstractVertebral artery hypoplasia (VAH) is a frequent anatomical variation of vertebral arteries, with emerging evidence suggesting that it contributes to posterior circulation ischemia. However, the relationship between VAH and ischemic stroke remains unknown. Hence, this study aimed to determine the prevalence of VAH in patients diagnosed with acute ischemic stroke who were followed up in a neurology clinic and to determine if it can potentially be a risk factor for atherosclerotic stenosis in vertebrobasilar circulation.This retrospective study included 609 patients diagnosed with acute ischemic stroke between January 1, 2019 and January 1, 2020. Demographic of patients, risk factors, radiological and clinical characteristics were evaluated.Posterior circulation was very common in patients with VAH, and the most common locations of atherosclerotic stenosis were V1 and V4 segments of the vertebral artery and the middle segment of basilar artery. Analysis of the risk factors for atherosclerotic stenosis in patients with posterior circulation acute ischemic stroke suggested that VAH was an independent risk factor.Findings of the study suggest that VAH pre-disposes atherosclerotic stenosis in vertebrobasilar circulation, although its mechanism remains unknown. Hemodynamic parameters associated with atherosclerosis could not be measured in vivo. Thus, to better understand the underlying mechanism, conducting studies that examine blood flow parameters with high-resolution magnetic resonance angiography in patients diagnosed with acute cerebral ischemia patients with VAH is warranted.
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Registered trials
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