Trial reportJMIR mHealth and uHealth2021
Effects of an Artificial Intelligence-Assisted Health Program on Workers With Neck/Shoulder Pain/Stiffness and Low Back Pain: Randomized Controlled Trial.
Trial report in JMIR mHealth and uHealth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 12 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 12 syntheses or guidelines pooled it, 115 citations in OpenAlex.
- Effectiveness of micro-exercises for managing neck/shoulder pain in sedentary workers: a systematic review and meta-analysis.Scientific reports · 2026Pooled it
- Artificial Intelligence in Physical, Occupational and Neuro-Rehabilitation: Clinical Effectiveness, Prognostic Performance, and Pre-Implementation Feasibility - A Systematic Review.Journal of medical systems · 2026Pooled it
- Do occupational health and safety tools that utilize artificial intelligence have a measurable impact on worker injury or illness? Findings from a systematic review.Systematic reviews · 2025Pooled it
- Moving towards the use of artificial intelligence in pain management.European journal of pain (London, England) · 2025Pooled it
- Effectiveness of AI-assisted rehabilitation for musculoskeletal disorders: a network meta-analysis of pain, range of motion, and functional outcomes.Frontiers in bioengineering and biotechnology · 2025Pooled it
- The multiple uses of artificial intelligence in exercise programs: a narrative review.Frontiers in public health · 2025Pooled it
- The effectiveness of digital interventions for self-management of chronic pain in employment settings: a systematic review.British medical bulletin · 2024Pooled it
- Impact of 25 Years of Mobile Health Tools for Pain Management in Patients With Chronic Musculoskeletal Pain: Systematic Review.Journal of medical Internet research · 2024Pooled it
- A systematic review and bayesian meta-analysis of medical devices used in chronic pain management.Scientific reports · 2024Pooled it
- Patient Engagement with Conversational Agents in Health Applications 2016-2022: A Systematic Review and Meta-Analysis.Journal of medical systems · 2024Pooled it
- Concordance of randomised controlled trials for artificial intelligence interventions with the CONSORT-AI reporting guidelines.Nature communications · 2024Pooled it
- Effects of Digital Physical Health Exercises on Musculoskeletal Diseases: Systematic Review With Best-Evidence Synthesis.JMIR mHealth and uHealth · 2024Pooled it
- Efficacy of a Mobile Multidisciplinary Digital Therapeutics App for Patellofemoral Pain: Randomized Controlled Trial.JMIR mHealth and uHealth · 2025Trial
- Clinical Efficacy of Multimodal Exercise Telerehabilitation Based on AI for Chronic Nonspecific Low Back Pain: Randomized Controlled Trial.JMIR mHealth and uHealth · 2025Trial
- Evaluation of the impact of AI-based chatbot on orthodontic patient education: a preliminary randomised controlled trial.Clinical oral investigations · 2025Trial
- Evaluation of the Effect of Patient Education and Strengthening Exercise Therapy Using a Mobile Messaging App on Work Productivity in Japanese Patients With Chronic Low Back Pain: Open-Label, Randomized, Parallel-Group Trial.JMIR mHealth and uHealth · 2022Trial
- Personalization of Training and Weight Reduction Using Artificial Intelligence: A Scoping Review of Current Evidence and Practical Limitations.Journal of functional morphology and kinesiology · 2026Review
- The Analytical Framework of Clinical Trials Evaluating Clinical Outcomes of Artificial Intelligence-Based Digital Health Interventions: A Systematic Literature Review.Journal of market access & health policy · 2026Review
- Effectiveness of Conversational Agents on Patient-Reported Outcomes in Chronic Pain Management: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2026Review
- Technology-Driven Ergonomics: A Narrative Review of Innovative Strategies for Preventing Musculoskeletal Disorders in Modern Work Environments.Health science reports · 2026Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMusculoskeletal symptoms such as neck and shoulder pain/stiffness and low back pain are common health problems in the working population. They are the leading causes of presenteeism (employees being physically present at work but unable to be fully engaged). Recently, digital interventions have begun to be used to manage health but their effectiveness has not yet been fully verified, and adherence to such programs is always a problem.
objectiveThis study aimed to evaluate the improvements in musculoskeletal symptoms in workers with neck/shoulder stiffness/pain and low back pain after the use of an exercise-based artificial intelligence (AI)-assisted interactive health promotion system that operates through a mobile messaging app (the AI-assisted health program). We expected that this program would support participants' adherence to exercises.
methodsWe conducted a two-armed, randomized, controlled, and unblinded trial in workers with either neck/shoulder stiffness/pain or low back pain or both. We recruited participants with these symptoms through email notifications. The intervention group received the AI-assisted health program, in which the chatbot sent messages to users with the exercise instructions at a fixed time every day through the smartphone's chatting app (LINE) for 12 weeks. The program was fully automated. The control group continued with their usual care routines. We assessed the subjective severity of the neck and shoulder pain/stiffness and low back pain of the participants by using a scoring scale of 1 to 5 for both the intervention group and the control group at baseline and after 12 weeks of intervention by using a web-based form. We used a logistic regression model to calculate the odds ratios (ORs) of the intervention group to achieve to reduce pain scores with those of the control group, and the ORs of the subjective assessment of the improvement of the symptoms compared to the intervention and control groups, which were performed using Stata software (version 16, StataCorp LLC).
resultsWe analyzed 48 participants in the intervention group and 46 participants in the control group. The adherence rate was 92% (44/48) during the intervention. The participants in the intervention group showed significant improvements in the severity of the neck/shoulder pain/stiffness and low back pain compared to those in the control group (OR 6.36, 95% CI 2.57-15.73; P<.001). Based on the subjective assessment of the improvement of the pain/stiffness at 12 weeks, 36 (75%) out of 48 participants in the intervention group and 3 (7%) out of 46 participants in the control group showed improvements (improved, slightly improved) (OR 43.00, 95% CI 11.25-164.28; P<.001).
conclusionsThis study shows that the short exercises provided by the AI-assisted health program improved both neck/shoulder pain/stiffness and low back pain in 12 weeks. Further studies are needed to identify the elements contributing to the successful outcome of the AI-assisted health program.
trial registrationUniversity hospital Medical Information Network-Clinical Trials Registry (UMIN-CTR) 000033894; https://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000038307.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.