Evidence map›Paper›PMID 34558871›Full record

ArticleYonsei medical journal2021

Modified Procedures for ALPPS Based on a Risk-Reduced Strategy: Paralleled Clinical Evaluation at Multiple Institutions.

Ya-Lin Kong, Ying Xing, Jie Li, Cheng-Li Liu, Xiao-Jun He, Cheng Wang, Jiang-Min Chen, Ling-Hong Kong, Xu Han, Hong-Yi Zhang

Open access · goldAbstract read
In one paragraph

Article in Yonsei medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Ya-Lin Kong *Department of Hepatobiliary Surgery, Chinese PLA Air Force Medical Center Affiliated to Air Force Military Medical University, Beijing, China. kjzygdwk@163.com.ORCID https://orcid.org/0000-0003-3783-5485
Ying Xing *Department of General Surgery, Tiantan Hospital Affiliated to Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0003-0792-6933
Jie LiDepartment of Hepatobiliary Surgery, Zibo Central Hospital, Zibo, China.ORCID https://orcid.org/0000-0001-7882-4091
Cheng-Li LiuDepartment of Hepatobiliary Surgery, Chinese PLA Air Force Medical Center Affiliated to Air Force Military Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-9654-7486
Xiao-Jun HeDepartment of Hepatobiliary Surgery, Chinese PLA Air Force Medical Center Affiliated to Air Force Military Medical University, Beijing, China.ORCID https://orcid.org/0000-0003-3580-8686
Cheng WangDepartment of Hepatobiliary Surgery, Chinese PLA Air Force Medical Center Affiliated to Air Force Military Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-4392-5113
Jiang-Min ChenDepartment of Hepatobiliary Surgery, Chinese PLA Air Force Medical Center Affiliated to Air Force Military Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-9768-1011
Ling-Hong KongDepartment of Hepatobiliary Surgery, Chinese PLA Air Force Medical Center Affiliated to Air Force Military Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-0219-6655
Xu HanDepartment of Hepatobiliary Surgery, Zibo Central Hospital, Zibo, China.ORCID https://orcid.org/0000-0002-6936-8984
Hong-Yi ZhangDepartment of General Surgery, Tiantan Hospital Affiliated to Capital Medical University, Beijing, China. zhhyiyi1487@163.com.ORCID https://orcid.org/0000-0002-2362-7805
Air Force General Hospital PLA · CNBeijing Tian Tan Hospital · CNCentral Hospital of Zibo · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe compared the clinical outcomes of modified procedures for associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) based on a risk-reduced strategy with those of classic ALPPS procedures in treating large liver carcinoma. MATERIALS AND

methodsShort-term outcomes, increases in future liver remnant (FLR) and functional FLR (FFLR), and overall survival (OS) were compared between 45 consecutive patients treated with modified ALPPS procedures and 34 patients treated with classic ALPPS procedures.

resultsClinical outcomes after the 1st-stage operation markedly improved with the modified procedures. Although the proportions of liver cirrhosis and hepatocellular carcinoma were higher in the modified group, the mortality and incidence of severe complications did not increase. FLR and FFLR hypertrophy at 1 week after the 1st-stage operation were similar in both groups; however, kinetic growth rates in the modified group were lower. OS rates were similar.

conclusionModified ALPPS procedures could be safely applied to provide long-term survival for patients with liver cirrhosis without sufficient FLR.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsHepatectomyHumansLigationLiverPortal VeinALPPScomplicationliver carcinomaliver cirrhosissurvival

Identifiers

PMID34558871
PMCPMC8470562
OpenAlexW3201026035

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.