Evidence map›Paper›PMID 34558639›Full record

ArticleInternational journal of oncology2021

miR‑383 increases the cisplatin sensitivity of lung adenocarcinoma cells through inhibition of the RBM24‑mediated NF‑κB signaling pathway.

Bo He, Chao Wu, Weichao Sun, Yang Qiu, Jingyao Li, Zhihui Liu, Tao Jing, Haidong Wang, Yi Liao

Open access · hybridAbstract read
In one paragraph

Article in International journal of oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Bo He *Department of Thoracic Surgery, Southwest Hospital, Army Medical University, Chongqing 400038, P.R. China.
Chao Wu *Department of Thoracic Surgery, Southwest Hospital, Army Medical University, Chongqing 400038, P.R. China.
Weichao SunThe Central Laboratory, Shenzhen Second People's Hospital, Shenzhen University First Affiliated Hospital, Shenzhen, Guangdong 518035, P.R. China.
Yang QiuDepartment of Thoracic Surgery, Southwest Hospital, Army Medical University, Chongqing 400038, P.R. China.
Jingyao LiDepartment of Thoracic Surgery, Southwest Hospital, Army Medical University, Chongqing 400038, P.R. China.
Zhihui LiuDepartment of Cardiology, Southwest Hospital, Army Medical University, Chongqing 400038, P.R. China.
Tao JingDepartment of Cardiology, Southwest Hospital, Army Medical University, Chongqing 400038, P.R. China.
Haidong WangDepartment of Thoracic Surgery, Southwest Hospital, Army Medical University, Chongqing 400038, P.R. China.
Yi LiaoDepartment of Thoracic Surgery, Southwest Hospital, Army Medical University, Chongqing 400038, P.R. China.
Southwest Hospital · CNArmy Medical University · CNShenzhen Second People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The expression of microRNA‑383 (miR‑383) is downregulated in a variety of tumor tissues, and it exhibits antiproliferative activity in non‑small cell lung cancer cells. In the present study, an association between the downregulation of miR‑383 expression and the deletion of chr8p22 in patients with lung adenocarcinoma was identified. The promoting effect of miR‑383 on cisplatin sensitivity was verified both

Indexed as

Adenocarcinoma of LungAdultAgedAged, 80 and overAnimalsCell Line, TumorCisplatinDrug Resistance, NeoplasmFemaleHumansLung NeoplasmsMaleMiceMice, Inbred BALB CMicroRNAsMiddle AgedCisplatinMicroRNAsMIRN383 microRNA, humanNF-kappa BRBM24 protein, humanRNA-Binding Proteinscisplatin resistancelung adenocarcinomamiR‑383NF‑κB signalingRBM24

Identifiers

PMID34558639
PMCPMC8460061
OpenAlexW3199928940

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.