Evidence map›Paper›PMID 34558299›Full record

ArticleCirculation. Heart failure2021

PD-L1 (Programmed Death Ligand 1) as a Marker of Acute Cellular Rejection After Heart Transplantation.

Arrush Choudhary, D Marshall Brinkley, Sepideh Besharati, Wouter C Meijers, James B Atkinson, Kaushik Amancherla, Qingfeng Zhu, Shi Huang, Lee S Nguyen, Joe-Elie Salem and 4 more

Abstract read
In one paragraph

Article in Circulation. Heart failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Elevated PD-L1 and PECAM-1 as Diagnostic Biomarkers of Acute Rejection in Lung Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
  12. Article
  13. Article
  14. Review
  15. [EJNMMI research · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Arrush ChoudharyDivision of Cardiology (A.C., D.M.B., W.C.M., K.A., J.-E.S., J.L., J.M.), Vanderbilt University Medical Center, Nashville, TN.
D Marshall BrinkleyDivision of Cardiology (A.C., D.M.B., W.C.M., K.A., J.-E.S., J.L., J.M.), Vanderbilt University Medical Center, Nashville, TN.ORCID 0000-0002-9511-7767
Sepideh BesharatiDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD (S.B., Q.Z., R.A.A.).
Wouter C MeijersDivision of Cardiology (A.C., D.M.B., W.C.M., K.A., J.-E.S., J.L., J.M.), Vanderbilt University Medical Center, Nashville, TN.
James B AtkinsonDepartment of Pathology (J.B.A.), Vanderbilt University Medical Center, Nashville, TN.
Kaushik AmancherlaDivision of Cardiology (A.C., D.M.B., W.C.M., K.A., J.-E.S., J.L., J.M.), Vanderbilt University Medical Center, Nashville, TN.ORCID 0000-0003-3379-5834
Qingfeng ZhuDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD (S.B., Q.Z., R.A.A.).
Shi HuangDepartment of Biostatistics (S.H.), Vanderbilt University Medical Center, Nashville, TN.
Lee S NguyenDepartment of Pharmacology, Sorbonne University, National Institute of Health and Medical Research, CIC-1901, Public Hospitals of Paris, UNICO-GRECO, Paris, France (L.S.N., J.-E.S.).ORCID 0000-0002-6014-6269
Joe-Elie SalemDivision of Cardiology (A.C., D.M.B., W.C.M., K.A., J.-E.S., J.L., J.M.), Vanderbilt University Medical Center, Nashville, TN.ORCID 0000-0002-0331-3307
Enrico AmmiratiDe Gasperis Cardio Center and Transplant Center, Niguarda Hospital, Milan, Italy (E.A.).ORCID 0000-0002-1676-5257
JoAnn LindenfeldDivision of Cardiology (A.C., D.M.B., W.C.M., K.A., J.-E.S., J.L., J.M.), Vanderbilt University Medical Center, Nashville, TN.
Robert A AndersDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD (S.B., Q.Z., R.A.A.).
Javid MoslehiDivision of Cardiology (A.C., D.M.B., W.C.M., K.A., J.-E.S., J.L., J.M.), Vanderbilt University Medical Center, Nashville, TN.ORCID 0000-0001-5443-4312

Funding

Immunologic and Antigenic Drivers of Immune Checkpoint Inhibitor-Associated MyocarditisR01HL156021 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Justin M Balko, Javid J Moslehi · 2021 to 2026
$4.9M
Novel mechanisms and predictors of VEGF receptor inhibitor-associated hypertensionR01HL141466 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MOSLEHI, JAVID J · 2019 to 2023
$3.3M
Long-Term Cardiovascular Sequelae of Cancer ImmunotherapiesR01HL155990 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI JOHNSON, DOUGLAS B, MOSLEHI, JAVID J · 2021 to 2025
$3.3M
NHLBI NIH HHS R01 HL141466NHLBI NIH HHS R01 HL155990NHLBI NIH HHS R01 HL156021
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultB7-H1 AntigenBiomarkersFemaleGraft RejectionHeart FailureHeart TransplantationHumansMaleProgrammed Cell Death 1 ReceptorYoung AdultB7-H1 AntigenBiomarkersCD274 protein, humanProgrammed Cell Death 1 Receptorbiopsygraft rejectionhumansmyocarditisupregulation

Identifiers

PMID34558299
PMCPMC8608373

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.