ArticleJournal of the American Heart Association2021
Surgery Is Underused in Elderly Patients With Left-Sided Infective Endocarditis: A Nationwide Registry Study.
Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 33 citations in OpenAlex.
- Long-term Oral Suppressive Antimicrobial Therapy in Infective Endocarditis (SATIE Study): An Observational Study.Open forum infectious diseases · 2024Trial
- Changing Patterns in Infective Endocarditis: A Contemporary Epidemiological Perspective.Pathogens (Basel, Switzerland) · 2026Review
- Recurrent Prosthetic Valve Endocarditis With Aortomitral Curtain Destruction in an Elderly Patient.JACC. Case reports · 2026Article
- Management and outcomes of infective endocarditis in a community hospital and its cardiac surgery referral centre.Scientific reports · 2026Article
- Cardiac valve prosthesis choice for left-sided infective endocarditis in Medicare patients.JTCVS open · 2026Article
- [Contemporary management of endocarditis].Herz · 2025Review
- Infective Endocarditis After TAVR-Surgical Challenges and Outcomes.Journal of clinical medicine · 2025Article
- Surgical and Clinical Aspects Associated with Double-Valve Infective Endocarditis.Journal of clinical medicine · 2025Article
- Infective endocarditis: it takes a team.European heart journal · 2025Review
- Epidemiological, clinical and microbiological aspects of infective endocarditis in Türkiye.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025Article
- Prognostic factors for long-term mortality after surgery of left-sided infective endocarditis.PloS one · 2025Article
- The Surgical Treatment of Infective Endocarditis: A Comprehensive Review.Diagnostics (Basel, Switzerland) · 2024Review
- It happened tomorrow-transcatheter treatments in the lifetime management of aortic valve diseases.Journal of visualized surgery · 2024Review
- Does Quality of Life in Survivors of Surgery for Acute Left-Sided Infective Endocarditis Differ from Non-Endocarditis Patients?Microorganisms · 2023Article
- Article
- Mid- and Long-Term Surgical Outcomes Due to Infective Endocarditis in Elderly Patients: A Retrospective Cohort Study.Journal of clinical medicine · 2022Article
- Surgery and outcome of infective endocarditis in octogenarians: prospective data from the ESC EORP EURO-ENDO registry.Infection · 2022Article
- Comorbidity and Prognosis in Octogenarians with Infective Endocarditis.Journal of clinical medicine · 2022Article
- Infective endocarditis in developing countries: An update.Frontiers in cardiovascular medicine · 2022Review
- Surgery Is Underused in Elderly Patients With Left-Sided Infective Endocarditis: A Nationwide Registry Study.Journal of the American Heart Association · 2021Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Infective endocarditis is associated with higher mortality in elderly patients, but the role of surgery in this group has not been fully evaluated. The aim of this study was to assess outcomes of left-sided infective endocarditis in elderly patients and to determine the influence of surgery on mortality in the elderly. Methods and Results A nationwide retrospective study was performed of 2186 patients with left-sided infective endocarditis recorded in the SRIE (Swedish Registry of Infective Endocarditis), divided into patients aged <65 years (n=864), 65 to 79 years (n=806), and ≥80 years (n=516). Survival analysis was performed using the Swedish National Population Registry, and propensity score matching was applied to assess the effect of surgery on survival among patients of all ages. The rate of surgery decreased with increasing age, from 46% in the <65 group to 6% in the ≥80 group. In-hospital mortality was 3 times higher in the ≥80 group compared with the <65 group (23% versus 7%) and almost twice that of the 65 to 79 group (12%). In propensity-matched groups, the mortality rate was significantly lower between the ages of 55 and 82 years in patients who underwent surgery compared with patients who did not undergo surgery. Surgery was also associated with better long-term survival in matched patients who were ≥75 years (hazard ratio, 0.36; 95% CI, 0.24-0.54 [
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