Evidence map›Paper›PMID 34557991›Full record

ArticleSurgical case reports2021

Burkitt-type lymphoma incidentally found as the cause of acute appendicitis: a case report and review of literature.

Davit Shahmanyan, Brian Saway, Hannah Palmerton, John S Rudderow, Christopher M Reed, Terri-Ann Wattsman, Emily R Faulks, Bryan R Collier, Robert E Budin, Mark E Hamill

Open access · goldAbstract read
In one paragraph

Article in Surgical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Davit ShahmanyanDepartment of Surgery, University of California San Francisco Fresno, 2823 Fresno St, Fresno, CA, 93701, USA.
Brian SawayDepartment of Neurosurgery, Medical University of South Carolina, 96 Jonathan Lucas Street, Charleston, SC, 29425, USA.
Hannah PalmertonDepartment of Surgery, Madigan Army Medical Center, 9040A Jackson Ave, Joint Base Lewis-McChord, WA, 98431, USA.
John S RudderowDepartment of Surgery, Virginia Tech Carilion School of Medicine and Research Institute, 3 Riverside Circle, Roanoke, VA, 24016, USA.
Christopher M ReedValley Health Bariatric and Metabolic Surgery Program, 1870 Amherst St, Winchester, VA, 22601, USA.
Terri-Ann WattsmanDepartment of Surgery, Virginia Tech Carilion School of Medicine and Research Institute, 3 Riverside Circle, Roanoke, VA, 24016, USA.
Emily R FaulksDepartment of Surgery, Virginia Tech Carilion School of Medicine and Research Institute, 3 Riverside Circle, Roanoke, VA, 24016, USA.
Bryan R CollierDepartment of Surgery, Virginia Tech Carilion School of Medicine and Research Institute, 3 Riverside Circle, Roanoke, VA, 24016, USA.
Robert E BudinDepartment of Surgery, Virginia Tech Carilion School of Medicine and Research Institute, 3 Riverside Circle, Roanoke, VA, 24016, USA.
Mark E HamillDepartment of Surgery, Virginia Tech Carilion School of Medicine and Research Institute, 3 Riverside Circle, Roanoke, VA, 24016, USA. hamillm@mac.com.ORCID http://orcid.org/0000-0001-9566-0009
Carilion Clinic · USMadigan Army Medical Center · USMedical University of South Carolina · USNebraska Medical Center · USUniversity of California, San Francisco · USValley Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAppendectomy remains one of the most common emergency operations. Recent research supports the treatment of uncomplicated appendicitis with antibiotics alone. While nonoperative management of appendicitis may be safe in some patients, it may result in missed neoplasms. We present a case of acute appendicitis where the final pathology resulted in a diagnosis of a Burkitt-type lymphoma. CASE PRESENTATION: An 18-year-old male presented to the emergency department with 24 h of right lower quadrant pain with associated urinary retention, anorexia, and malaise. Past medical history was significant for intermittent diarrhea and anal fissure. He exhibited focal right lower quadrant tenderness. Workup revealed leukocytosis and CT uncovered acute appendicitis with periappendiceal abscess and no appendicolith. Laparoscopic appendectomy was performed and found acute appendicitis with associated abscess abutting the rectum and bladder. Pathology of the resected appendix reported acute appendicitis with evidence of Burkitt-type lymphoma. A PET scan did not reveal any residual disease. Hematology/oncology was consulted and chemotherapy was initiated with an excellent response.

conclusionsAppendiceal lymphomas constitute less than 0.1% of gastrointestinal lymphomas. Primary appendix neoplasms are found in 0.5-1.0% of appendectomy specimens following acute appendicitis. In this case, appendectomy allowed for prompt identification and treatment of an aggressive, rapidly fatal lymphoma resulting in complete remission.

Indexed as

Acute appendicitisBurkitt lymphomaIncidental findingSurgical pathology

Identifiers

PMID34557991
PMCPMC8460683
OpenAlexW3198980684

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.