Evidence map›Paper›PMID 34557972›Full record

ReviewEJNMMI research2021

Imaging modalities for diagnosis and monitoring of cancer cachexia.

Jessie Han, Luke Harrison, Lisa Patzelt, Mingming Wu, Daniela Junker, Stephan Herzig, Mauricio Berriel Diaz, Dimitrios C Karampinos

Open access · goldAbstract readReview
In one paragraph

Review in EJNMMI research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Defining Cachexia in Children With Cancer in the United States: Developing a Framework to Inform Clinical and Research Practice.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026
    Article
  5. Review
  6. Article
  7. Assessment of Lean body mass using whole-body low-dose Ct from Pet/Ct to identify cancer Cachexia.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Multimodal AI-driven Biomarker for Early Detection of Cancer Cachexia.medRxiv : the preprint server for health sciences · 2025
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Drosophila Intestine as a Model to Study Tumors.Advances in experimental medicine and biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jessie HanDepartment of Diagnostic and Interventional Radiology, Klinikum Rechts Der Isar, TUM School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany. jessie.han@tum.de.ORCID http://orcid.org/0000-0001-6008-4195
Luke HarrisonInstitute for Diabetes and Cancer, Helmholtz Center Munich, 85764, Neuherberg, Germany.
Lisa PatzeltDepartment of Diagnostic and Interventional Radiology, Klinikum Rechts Der Isar, TUM School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany.
Mingming WuDepartment of Diagnostic and Interventional Radiology, Klinikum Rechts Der Isar, TUM School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany.
Daniela JunkerDepartment of Diagnostic and Interventional Radiology, Klinikum Rechts Der Isar, TUM School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany.
Stephan HerzigInstitute for Diabetes and Cancer, Helmholtz Center Munich, 85764, Neuherberg, Germany.
Mauricio Berriel DiazInstitute for Diabetes and Cancer, Helmholtz Center Munich, 85764, Neuherberg, Germany.
Dimitrios C KarampinosDepartment of Diagnostic and Interventional Radiology, Klinikum Rechts Der Isar, TUM School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany.
TUM Klinikum · DEDeutsches Diabetes-Zentrum e.V. · DEHeidelberg University · DE

Funding

deutsche forschungsgemeinschaft SFB824/A9
6 · The paper itself

Abstract

Cachexia, a multifactorial wasting syndrome, is highly prevalent among advanced-stage cancer patients. Unlike weight loss in healthy humans, the progressive loss of body weight in cancer cachexia primarily implicates lean body mass, caused by an aberrant metabolism and systemic inflammation. This may lead to disease aggravation, poorer quality of life, and increased mortality. Timely detection is, therefore, crucial, as is the careful monitoring of cancer progression, in an effort to improve management, facilitate individual treatment and minimize disease complications. A detailed analysis of body composition and tissue changes using imaging modalities-that is, computed tomography, magnetic resonance imaging, (

Indexed as

Adipose tissueCancer cachexia progressionComputed tomography (CT)Imaging-based phenotypingImaging biomarkersMagnetic resonance imaging (MRI)Skeletal muscle

Identifiers

PMID34557972
PMCPMC8460705
OpenAlexW3201437644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.