Evidence map›Paper›PMID 34557927›Full record

ArticleScandinavian journal of work, environment & health2022

Night and shift work and incidence of cerebrovascular disease - a prospective cohort study of healthcare employees in Stockholm.

Carolina Bigert, Manzur Kader, Tomas Andersson, Jenny Selander, Theo Bodin, Per Gustavsson, Mikko Härmä, Petter Ljungman, Maria Albin

Open access · goldAbstract read
In one paragraph

Article in Scandinavian journal of work, environment & health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.

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  12. Working hours and health - key research topics in the past and future.Scandinavian journal of work, environment & health · 2024
    Review
  13. Working hours and cardiovascular disease.Scandinavian journal of work, environment & health · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Carolina BigertInstitute of Environmental Medicine, Karolinska Institutet, Solnavägen 4 10th floor, SE-113 65 Stockholm, Sweden. carolina.bigert@ki.se.
Manzur Kader
Tomas Andersson
Jenny Selander
Theo Bodin
Per Gustavsson
Mikko Härmä
Petter Ljungman
Maria Albin
Karolinska Institutet · SEFinnish Institute of Occupational Health · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to investigate the effects of various aspects of night and shift work regarding incident cerebrovascular disease (CeVD).

methodsThe cohort included 26 667 women and 3793 men (nurses and nursing assistants) who were employed for at least one year 2008-2016 in Region Stockholm, Sweden. Information about the cohort and working hours were obtained from a computerized employee-register and diagnoses were retrieved from national and regional registers. We used discrete time proportional hazard models to assess the risk of CeVD (2009-2017), in relation to work hour characteristics, adjusting for sex, age, country of birth, education and profession.

resultsWe observed an excess risk of CeVD (N=223) among employees who, during the preceding year, worked night shifts >30 times [hazard ratio (HR) 1.44, 95% confidence interval (CI) 1.04-1.99] or ≥3 consecutive night shifts >15 times (HR 1.69, 95% CI 1.18-2.42) or with >30 quick returns (<28 hours) from night shifts (HR 1.52, 95% CI 1.10-2.10) compared to those who did not work nights. We also observed an excess risk among employees with a long duration (>5 years) of exposure to night shift work (HR 1.87, 95% CI 1.27-2.77), all supported by a dose-response pattern.

conclusionsOur results show that the risk of CeVD among nurses and nursing assistants is associated with night shift work. The number of years with night shift work, the frequency of night shifts per year, the frequency of consecutive night shifts, and short recovery after night shifts influenced the risk. Work schedules aiming at minimizing these aspects of night shift work may reduce the risk.

Indexed as

Cerebrovascular DisordersShift Work ScheduleCohort StudiesDelivery of Health CareFemaleHumansIncidenceMalePersonnel, HospitalProspective StudiesRisk FactorsWork Schedule Tolerance

Identifiers

PMID34557927
PMCPMC8729165
OpenAlexW3199806010

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.