Evidence map›Paper›PMID 34557859›Full record

ArticleThe Lancet regional health. Europe2021

Quality of life among people living with HIV in England and the Netherlands: a population-based study.

Stephanie Popping, Meaghan Kall, Brooke E Nichols, Evelien Stempher, Lisbeth Versteegh, David A M C van de Vijver, Ard van Sighem, M Versteegh, Charles Boucher, Valerie Delpech and 1 more

Abstract read
In one paragraph

Article in The Lancet regional health. Europe, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. An international compendium of health state utilities in people with HIV: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Stephanie PoppingErasmus Medical Centre, Rotterdam, Department of Viroscience, The Netherlands.
Meaghan KallHIV and STI Department, National Infection Service, Public Health England, London, United Kingdom.
Brooke E NicholsErasmus Medical Centre, Rotterdam, Department of Viroscience, The Netherlands.
Evelien StempherErasmus Medical Centre, Rotterdam, Department of Viroscience, The Netherlands.
Lisbeth VersteeghErasmus Medical Centre, Rotterdam, Department of Viroscience, The Netherlands.
David A M C van de VijverErasmus Medical Centre, Rotterdam, Department of Viroscience, The Netherlands.
Ard van SighemStichting HIV monitoring, Amsterdam, The Netherlands.
M Versteeghinstitute for Medical Technology Assessment (iMTA), Erasmus University Rotterdam.
Charles BoucherErasmus Medical Centre, Rotterdam, Department of Viroscience, The Netherlands.
Valerie DelpechHIV and STI Department, National Infection Service, Public Health England, London, United Kingdom.
Annelies VerbonErasmus Medical Centre, Rotterdam, Department of Medical Microbiology and Infectious Diseases.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHIV is now considered a chronic condition, and people living with HIV, when treated, have a similar life expectancy as compared to the general population. Consequently, improving and ensuring a good health-related quality of life (HrQoL) among people living with HIV (people living with HIV) is increasingly important and has risen on the global agenda in recent years. A 'fourth 90' as 90% of people with viral load suppression have a good HrQoL should therefore be adopted alongside the other 90-90-90 targets. This study aims to report the progress on HrQoL as the 'fourth 90' and compare against the general population in the Netherlands and England.

methodsIn the Netherlands, individuals attending the HIV outpatient clinic of a tertiary hospital were asked to complete the EQ-5D-5L from June 2016 until December 2018. In England, individuals attending one of 73 HIV outpatient clinics were randomly sampled to complete the Positive Voices survey, which included the EQ-5D-5L, from January to September 2017. HrQoL scores were combined with demographic data and compared to general population data.

findingsThe EQ-5D-5L was filled-out by 895 people living with HIV in the NL and 4,137 in England. HrQoL

interpretationOverall, HrQoL

fundingThe study received funding (unrestricted grants) from: Gilead sciences, ViiV Healthcare, MSD, and Jansen pharmaceuticals.

Indexed as

elimination goalsHIVpeople living with HIVquality of lifevalue-based healthcare

Identifiers

PMID34557859
PMCPMC8454587

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.