ArticleThe Lancet regional health. Europe2021
Properties of the EQ-5D-5L when prospective longitudinal data from 28,902 total hip arthroplasty procedures are applied to different European EQ-5D-5L value sets.
Article in The Lancet regional health. Europe, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Factors contributing to 1-year dissatisfaction after total knee arthroplasty: a nomogram prediction model.Journal of orthopaedic surgery and research · 2022Trial
- Cost-effectiveness of a structured medication review approach for multimorbid older adults: Within-trial analysis of the OPERAM study.PloS one · 2022Trial
- Changes in health-related quality of life: a longitudinal registry study among over 15,000 participants of a digital education and exercise therapy for knee and hip osteoarthritis using EQ-5D-5L.Health and quality of life outcomes · 2026Article
- Article
- Article
- Changes in quality of life and work status after surgical management of meralgia paresthetica- an observational cohort study.Brain & spine · 2026Article
- Caregivers' Perceptions of Clinical Symptoms, Disease Management, and Quality of Life Impact in Cases of Cyclin-Dependent Kinase-Like 5 Deficiency Disorder: Cross-Sectional Online Survey.JMIR formative research · 2025Article
- Health consequences of graded, full, and no sickness absence among workers with musculoskeletal disorders: health profiles and six-months symptom changes of patients referred to Norwegian outpatient clinics for chronic neck and back pain.BMC musculoskeletal disorders · 2025Article
- Cohort profile: the Norwegian Neck and Back Registry (NNRR): a medical quality registry for patients with neck and back complaints.BMJ open · 2025Article
- COST AND QUALITY OF LIFE IN PATIENTS UNDERWENT HIP ARTHROPLASTY IN A BRAZILIAN HOSPITAL.Acta ortopedica brasileira · 2025Article
- Braving the waves: exploring capability well-being patterns in seven European countries during the COVID-19 pandemic.The European journal of health economics : HEPAC : health economics in prevention and care · 2024Observational
- Patient acceptable symptom state and treatment failure threshold values for work productivity and activity Impairment and EQ-5D-5L in osteoarthritis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Evaluation of the EQ-5D-5L, EQ-VAS stand-alone component and Oxford knee score in the Australian knee arthroplasty population utilising minimally important difference, concurrent validity, predictive validity and responsiveness.Health and quality of life outcomes · 2023Article
- Healthcare Costs and Health-Related Quality of Life in Older Multimorbid Patients After Hospitalization.Health services insights · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this study was to evaluate the impact of using different country-specific value sets in EQ-5D-5L based outcome analyses.
methodsWe obtained data on patients surgically treated with total hip arthroplasty (THA) between 2017 and 2019 from the national Swedish Hip Arthroplasty Register. Preoperative and one-year postoperative data on a total of 28,902 procedures were available for analysis. The EQ-5D-5L health states were coded to the EQ-5D-5L preference indices using 13 European value sets. The EQ-5D-5L index distributions were then estimated with kernel density estimation. The change in EQ-5D-5L index before and one year after treatment was evaluated with the standardized response mean (SRM). The lifetime gain in quality-adjusted life years (QALYs) was estimated with a 3.5% annual QALY discount rate.
findingsThere was a marked variability in means and shapes of the resulting EQ-5D-5L index distributions. There were also considerable differences in the EQ-5D-5L index distribution shape before and after the treatment using the same value set. The effect sizes of one-year change (SRM) were similar for all value sets. However, the differences in estimated QALY gains were substantial.
interpretationThe EQ-5D-5L index distributions varied considerably when a single large data set was applied to different European EQ-5D-5L value sets. The most pronounced differences were between the value sets based on experience-based valuation and the value sets based on hypothetical valuation. This illustrates that experience-based and hypothetical value sets are inherently different and also that QALY gains derived with different value sets are not comparable. Our findings are of importance in study planning since the results and conclusions of a study depend on the choice of value set.
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