Evidence map›Paper›PMID 34557762›Full record

ArticleInnovation (Cambridge (Mass.))2021

Impact of immunization programs on 11 childhood vaccine-preventable diseases in China: 1950-2018.

Jinhua Pan, Yesheng Wang, Lingsheng Cao, Ying Wang, Qi Zhao, Shenglan Tang, Wenfeng Gong, Lei Guo, Zhixi Liu, Zexuan Wen and 2 more

Abstract read
In one paragraph

Article in Innovation (Cambridge (Mass.)), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  17. Global vaccine coverage and childhood survival estimates: 1990-2019.Bulletin of the World Health Organization · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jinhua PanDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China.
Yesheng WangDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China.
Lingsheng CaoNational Immunization Program, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Ying WangDepartment of Social Medicine, School of Public Health, Fudan University, Shanghai 200032, China.
Qi ZhaoDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China.
Shenglan TangDuke Global Health Institute, Duke University, Durham, NC 27708, USA.
Wenfeng GongBill and Melinda Gates Foundation, Seattle, WA 98109, USA.
Lei GuoDuke Global Health Institute, Duke University, Durham, NC 27708, USA.
Zhixi LiuDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China.
Zexuan WenDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China.
Bo ZhengDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China.
Weibing WangDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the achievements of China's immunization program between 1950 and 2018, we chose 11 vaccine-preventable diseases (VPDs) as representative notifiable diseases and used annual surveillance data obtained between 1950 and 2018 to derive disease incidence and mortality trends. Quasi-Poisson and polynomial regression models were used to estimate the impacts of specific vaccine programs, and life-table methods were used to calculate the loss of life expectancy, years of life lost, and loss of working years. The total notification number for the 11 VPDs was 211,866,000 from 1950 to 2018. The greatest number occurred in 1959, with a total incidence of 1,723 per million persons. From 1978 to 2018, a substantial decline was observed in the incidence of major infectious diseases. The incidence of pertussis fell 98% from 126.35 to 1.58 per million, and the incidences of measles, meningococcal meningitis, and Japanese encephalitis fell 99%, 99%, and 98%, respectively. The regression models showed that most of the 11 diseases exhibited dramatic declines in morbidity after their integration into the Expanded Program on Immunization (EPI), while varicella and paratyphoid fever, which were not integrated into the EPI, showed increased morbidity. From 1978 to 2018, the total life expectancy for the 11 VPDs increased by 0.79 years, and similar results were obtained for different age groups. China has had great success in controlling VPDs in recent decades, and improving vaccination coverage is a key aspect of controlling VPDs in China.

Indexed as

Chinaimmunizationmorbiditymortalityvaccine-preventable diseases

Identifiers

PMID34557762
PMCPMC8454656

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.